Evidence map›Paper›PMID 25245428›Full record

ArticleJournal of substance abuse treatment2015

Prescription medication misuse among HIV-infected individuals taking antiretroviral therapy.

Howard Newville, Jason Roley, James L Sorensen

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. HIV and Substance Use Disorders.Infectious disease clinics of North America · 2024
    Review
  2. Article
  3. Social Contact Frequency and Pain among Older Adults with HIV: An Ecological Momentary Assessment Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prescription drug abuse: from epidemiology to public policy.Journal of substance abuse treatment · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Howard NewvilleMount Sinai St. Luke's, New York, NY, United States.
Jason RoleyUniversity of California, San Francisco, San Francisco, CA, United States.
James L SorensenUniversity of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USSt. Luke's Hospital · US

Funding

TREATMENTS FOR COMPLEX PATIENTS IN NEW SETTINGSP50DA009253 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GUYDISH, JOSEPH R · 1994 to 2014
$28.2M
Improving HAART adherence in HIV+ active drug usersF32DA032446 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEWVILLE, HOWARD · 2011 to 2012
$94k
NIDA NIH HHS F32 DA032446NIDA NIH HHS F32DA032446NIDA NIH HHS P50 DA009253NIDA NIH HHS P50DA09253
6 · The paper itself

Abstract

HIV has become a highly treatable disease due to advances in antiretroviral therapy (ART). Additionally, HIV-infected individuals often take opiates, barbiturates, and benzodiazepines to treat co-occurring conditions, including pain and symptoms of HIV. We sought to examine prescription medication misuse by surveying 295 HIV-infected patients receiving ART. Participants answered questions about their demographics, alcohol and other drug use, psychiatric diagnoses, ART adherence and side effects, and quality of life. Eleven percent of our sample acknowledged prescription medication misuse. In regression analysis, prescription medication misusers were more likely to report any drinking to intoxication (OR=4.31, 95% CI: 1.35-13.76, p=0.013), reported greater severity of ART side effects (OR=1.05, 95% CI: 1.01-1.10, p=0.041), and demonstrated poorer cognitive functioning (OR=0.97, 95% CI: 0.94-0.99, p=0.048) compared to those who did not misuse prescription medications. Special care should be taken by medical providers before prescribing medications that may be abused or diverted. Patients should also be screened for aberrant use, even if not prescribed. ART side effects, cognitive deficits, and alcohol abuse may serve as risk factors or indicators of prescription medication misuse, and should be monitored.

Indexed as

AdultAntiretroviral Therapy, Highly ActiveFemaleHIV InfectionsHumansMaleMiddle AgedPrescription Drug MisuseSeverity of Illness IndexSubstance-Related DisordersAntiretroviral therapyHIVPrescription medication misuse

Identifiers

PMID25245428
PMCPMC4250322
OpenAlexW2032180630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.