ArticleJournal of magnetic resonance imaging : JMRI2015
T2 Relaxation time quantitation differs between pulse sequences in articular cartilage.
Article in Journal of magnetic resonance imaging : JMRI, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2019Pooled it
- Reproducibility of T2 relaxation time mapping in a phantom and human knee articular cartilage.Magma (New York, N.Y.) · 2026Article
- Assessing the Impact of Imaging Parameters on MRI Measurement of Kidney TJournal of magnetic resonance imaging : JMRI · 2026Article
- RF phase modulation improves quantitative transient state sequences under constrained conditions.Magma (New York, N.Y.) · 2026Article
- Prospective study assessing the validity of accelerated 2D Fast Spin Echo (2D FSE) based high-resolution knee MRI and T2 mapping using deep learning reconstruction.BMC musculoskeletal disorders · 2026Article
- Exercise-Induced Changes in Knee Cartilage In Vivo: Comparing MRI Sequences.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Diagnostic Value of T2 Mapping in Sacroiliitis Associated with Spondyloarthropathy.Diagnostics (Basel, Switzerland) · 2025Article
- Super-resolution synthetic MRI using deep learning reconstruction for accurate diagnosis of knee osteoarthritis.Insights into imaging · 2025Article
- Feasibility of 3D MRI fingerprinting for rapid knee cartilage TNMR in biomedicine · 2024Article
- A straightforward procedure to build a non-toxic relaxometry phantom with desired T1 and T2 times at 3T.Magma (New York, N.Y.) · 2024Article
- The design of a sample rapid magnetic resonance imaging (MRI) acquisition protocol supporting assessment of multiple articular tissues and pathologies in knee osteoarthritis.Osteoarthritis and cartilage open · 2024Article
- Characterization of acute effects of football competition on hamstring muscles by muscle functional MRI techniques.PloS one · 2024Article
- Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI.European radiology experimental · 2023Article
- MRI-based TSkeletal radiology · 2023Review
- Optimizing variable flip angles in magnetization-prepared gradient-echo sequences for efficient 3D-T1ρ mapping.Magnetic resonance in medicine · 2023Article
- Insights into the Age Dependency of Compositional MR Biomarkers Quantifying the Health Status of Cartilage in Metacarpophalangeal Joints.Diagnostics (Basel, Switzerland) · 2023Article
- Application of quantitative T1, T2 and T2* mapping magnetic resonance imaging in cartilage degeneration of the shoulder joint.Scientific reports · 2023Article
- Early knee OA definition-what do we know at this stage? An imaging perspective.Therapeutic advances in musculoskeletal disease · 2023Review
- MR relaxation times of agar-based tissue-mimicking phantoms.Journal of applied clinical medical physics · 2022Article
- TSkeletal radiology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundTo compare T2 relaxation time measurements between MR pulse sequences at 3 Tesla in agar phantoms and in vivo patellar, femoral, and tibial articular cartilage.
methodsT2 relaxation times were quantified in phantoms and knee articular cartilage of eight healthy individuals using a single echo spin echo (SE) as a reference standard and five other pulse sequences: multi-echo SE (MESE), fast SE (2D-FSE), magnetization-prepared spoiled gradient echo (3D-MAPSS), three-dimensional (3D) 3D-FSE with variable refocusing flip angle schedules (3D vfl-FSE), and quantitative double echo steady state (qDESS). Cartilage was manually segmented and average regional T2 relaxation times were obtained for each sequence. A regression analysis was carried out between each sequence and the reference standard, and root-mean-square error (RMSE) was calculated.
resultsPhantom measurements from all sequences demonstrated strong fits (R(2) > 0.8; P < 0.05). For in vivo cartilage measurements, R(2) values, slope, and RMSE were: MESE: 0.25/0.42/5.0 ms, 2D-FSE: 0.64/1.31/9.3 ms, 3D-MAPSS: 0.51/0.66/3.8 ms, 3D vfl-FSE: 0.30/0.414.2 ms, qDESS: 0.60/0.90/4.6 ms.
conclusion2D-FSE, qDESS, and 3D-MAPSS demonstrated the best fits with SE measurements as well as the greatest dynamic ranges. The 3D-MAPSS, 3D vfl-FSE, and qDESS demonstrated the closest average measurements to SE. Discrepancies in T2 relaxation time quantitation between sequences suggest that care should be taken when comparing results between studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.