ArticleJournal of cognitive neuroscience2015
Asymmetric connectivity between the anterior temporal lobe and the language network.
Article in Journal of cognitive neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Task-Free Functional Language Networks: Reproducibility and Clinical Application.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Pooled it
- The Anterior Temporal Semantic Hub in the Left and Right Hemispheres: A Unitary System or Two Separate Systems for Meaning?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Anterior temporal lobe, word comprehension, and physiology of atrophy in semantic primary progressive aphasia.Neurocase · 2025Article
- Disentangling phonology from phonological short-term memory in Alzheimer's disease phenotypes.Alzheimer's research & therapy · 2025Article
- Spatial and Temporal Progression of Neurodegeneration in Confirmed and Suspected TDP-43 Type C Pathology.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The developing Human Connectome Project fetal functional MRI release: Methods and data structures.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Free-water imaging reveals unique brain microstructural deficits in hispanic individuals with Dementia.Brain imaging and behavior · 2024Article
- Semantic representations in inferior frontal and lateral temporal cortex during picture naming, reading, and repetition.Human brain mapping · 2024Article
- Temporopolar regions of the human brain.Brain : a journal of neurology · 2023Article
- Are alpha and beta oscillations spatially dissociated over the cortex in context-driven spoken-word production?Psychophysiology · 2022Article
- Stimulation of distinct parietal locations differentiates frontal versus hippocampal network involvement in memory formation.Current research in neurobiology · 2022Article
- Characterizing Differences in Functional Connectivity Between Posterior Cortical Atrophy and Semantic Dementia by Seed-Based Approach.Frontiers in aging neuroscience · 2022Article
- Modularity and granularity across the language network-A primary progressive aphasia perspective.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Nosology of Primary Progressive Aphasia and the Neuropathology of Language.Advances in experimental medicine and biology · 2021Article
- Cognitive and Structural Correlates of Conversational Speech Timing in Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease: Relevance for Early Detection Approaches.Frontiers in aging neuroscience · 2021Article
- Characteristics of resting-state functional connectivity in older adults after the PICMOR intervention program: a preliminary report.BMC geriatrics · 2020Article
- Convergence of distinct functional networks supporting naming and semantic recognition in the left inferior frontal gyrus.Human brain mapping · 2020Article
- Principles of temporal association cortex organisation as revealed by connectivity gradients.Brain structure & function · 2020Article
- Functional Connectivity Alterations of the Temporal Lobe and Hippocampus in Semantic Dementia and Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2020Article
- Perturbations of language network connectivity in primary progressive aphasia.Cortex; a journal devoted to the study of the nervous system and behavior · 2019Article
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4 authors.
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Abstract
The anterior temporal lobe (ATL) sits at the confluence of auditory, visual, olfactory, transmodal, and limbic processing hierarchies. In keeping with this anatomical heterogeneity, the ATL has been implicated in numerous functional domains, including language, semantic memory, social cognition, and facial identification. One question that has attracted considerable discussion is whether the ATL contains a mosaic of differentially specialized areas or whether it provides a domain-independent amodal hub. In the current study, based on task-free fMRI in right-handed neurologically intact participants, we found that the left lateral ATL is interconnected with hubs of the temporosylvian language network, including the inferior frontal gyrus and middle temporal gyrus of the ipsilateral hemisphere and, to a lesser extent, with homotopic areas of the contralateral hemisphere. In contrast, the right lateral ATL had much weaker functional connectivity with these regions in either hemisphere. Together with evidence that has been gathered in lesion-mapping and event-related neuroimaging studies, this asymmetry of functional connectivity supports the inclusion of the left ATL within the language network, a relationship that had been overlooked by classic aphasiology. The asymmetric domain selectivity for language of the left ATL, together with the absence of such an affiliation in the right ATL, is inconsistent with a strict definition of domain-independent amodal functionality in this region of the brain.
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