Evidence map›Paper›PMID 25243536›Full record

Trial reportJAMA pediatrics2014

Effects of aerobic training, resistance training, or both on percentage body fat and cardiometabolic risk markers in obese adolescents: the healthy eating aerobic and resistance training in youth randomized clinical trial.

Ronald J Sigal, Angela S Alberga, Gary S Goldfield, Denis Prud'homme, Stasia Hadjiyannakis, Réjeanne Gougeon, Penny Phillips, Heather Tulloch, Janine Malcolm, Steve Doucette and 3 more

Erratum issued Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in JAMA pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00195858 (Healthy Eating, Aerobic and Resistance Training in Youth), which is not on this map. Cited by 95 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 17 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00195858 phase2 / phase3completednot on this map

Healthy Eating, Aerobic and Resistance Training in Youth (HEARTY) Trial

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2005 to 2011Enrolled304ConditionsObesityArmsaerobic and resistance exercise
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 17 syntheses or guidelines pooled it, 182 citations in OpenAlex.

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  5. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  6. Managing obesity in children: a clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Ronald J SigalDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada2Department of Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada3Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada4Faculties of M.
Angela S AlbergaSchool of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada7Werklund School of Education, University of Calgary, Calgary, Alberta, Canada.
Gary S GoldfieldHealthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
Denis Prud'hommeInstitut de Recherche de l'Hôpital Montfort, Ottawa, Ontario, Canada.
Stasia HadjiyannakisHealthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
Réjeanne GougeonCrabtree Laboratories, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
Penny PhillipsClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Heather TullochPrevention and Rehabilitation Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Janine MalcolmClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Steve DoucetteDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
George A WellsCardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Jinhui MaResearch Institute, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Glen P KennyClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada6School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
Children's Hospital of Eastern Ontario · CAUniversity of Ottawa · CAOttawa Hospital · CAUniversity of Calgary · CADalhousie University · CAMontfort Hospital · CARoyal Victoria Regional Health Centre · CA

Funding

Canadian Institutes of Health Research MCT-71979
6 · The paper itself

Abstract

importanceLittle evidence exists on which exercise modality is optimal for obese adolescents.

objectiveTo determine the effects of aerobic training, resistance training, and combined training on percentage body fat in overweight and obese adolescents. DESIGN, SETTING, AND

participantsRandomized, parallel-group clinical trial at community-based exercise facilities in Ottawa (Ontario) and Gatineau (Quebec), Canada, among previously inactive postpubertal adolescents aged 14 to 18 years (Tanner stage IV or V) with body mass index at or above the 95th percentile for age and sex or at or above the 85th percentile plus an additional diabetes mellitus or cardiovascular risk factor.

interventionsAfter a 4-week run-in period, 304 participants were randomized to the following 4 groups for 22 weeks: aerobic training (n = 75), resistance training (n = 78), combined aerobic and resistance training (n = 75), or nonexercising control (n = 76). All participants received dietary counseling, with a daily energy deficit of 250 kcal. MAIN OUTCOMES AND MEASURES: The primary outcome was percentage body fat measured by magnetic resonance imaging at baseline and 6 months. We hypothesized that aerobic training and resistance training would each yield greater decreases than the control and that combined training would cause greater decreases than aerobic or resistance training alone.

resultsDecreases in percentage body fat were -0.3 (95% CI, -0.9 to 0.3) in the control group, -1.1 (95% CI, -1.7 to -0.5) in the aerobic training group (P = .06 vs controls), and -1.6 (95% CI, -2.2 to -1.0) in the resistance training group (P = .002 vs controls). The -1.4 (95% CI, -2.0 to -0.8) decrease in the combined training group did not differ significantly from that in the aerobic or resistance training group. Waist circumference changes were -0.2 (95% CI, -1.7 to 1.2) cm in the control group, -3.0 (95% CI, -4.4 to -1.6) cm in the aerobic group (P = .006 vs controls), -2.2 (95% CI -3.7 to -0.8) cm in the resistance training group (P = .048 vs controls), and -4.1 (95% CI, -5.5 to -2.7) cm in the combined training group. In per-protocol analyses (≥ 70% adherence), the combined training group had greater changes in percentage body fat (-2.4, 95% CI, -3.2 to -1.6) vs the aerobic group (-1.2; 95% CI, -2.0 to -0.5; P = .04 vs the combined group) but not the resistance group (-1.6; 95% CI, -2.5 to -0.8). CONCLUSIONS AND RELEVANCE: Aerobic, resistance, and combined training reduced total body fat and waist circumference in obese adolescents. In more adherent participants, combined training may cause greater decreases than aerobic or resistance training alone.

trial registrationclinicaltrials.gov Identifier: NCT00195858.

Indexed as

ExerciseResistance TrainingAdipose TissueAdolescentBlood GlucoseBody Mass IndexFemaleGlycated HemoglobinHumansInsulinLipidsMagnetic Resonance ImagingMalePediatric ObesityRisk FactorsWaist CircumferenceBlood GlucoseGlycated HemoglobinInsulinLipids

Identifiers

PMID25243536
OpenAlexW2016452229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.