ArticleACS macro letters2014
Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP.
Article in ACS macro letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Synthesis of Bottlebrush Polymers with Spontaneous Self-Assembly for Dielectric Generators.ACS applied polymer materials · 2024Article
- Anti-Obesity Drug Delivery Systems: Recent Progress and Challenges.Pharmaceutics · 2023Review
- Hydrogen Peroxide-Triggered Disassembly of Boronic Ester-Cross-Linked Brush-Arm Star Polymers.ACS macro letters · 2023Article
- Polymeric Nanotubes as Drug Delivery Vectors─Comparison of Covalently and Supramolecularly Assembled Constructs.Biomacromolecules · 2022Article
- Convergent Synthesis of Branched Metathesis Polymers with Enyne Reagents.Macromolecules · 2021Article
- Pro-organic radical contrast agents ("pro-ORCAs") for real-time MRI of pro-drug activation in biological systems.Polymer chemistry · 2020Article
- Oleic Acid Copolymer as A Novel Upconversion Nanomaterial to Make Doxorubicin-Loaded Nanomicelles with Dual Responsiveness to pH and NIR.Pharmaceutics · 2020Article
- Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer.Pharmaceutics · 2020Review
- Tumor Microenvironment-Stimuli Responsive Nanoparticles for Anticancer Therapy.Frontiers in molecular biosciences · 2020Review
- Preparation of Biomolecule-Polymer Conjugates by Grafting-From Using ATRP, RAFT, or ROMP.Progress in polymer science · 2020Article
- Tailored silyl ether monomers enable backbone-degradable polynorbornene-based linear, bottlebrush and star copolymers through ROMP.Nature chemistry · 2019Article
- Ionic Polymethacrylate Based Delivery Systems: Effect of Carrier Topology and Drug Loading.Pharmaceutics · 2019Review
- Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents.ACS macro letters · 2019Article
- Enhanced Oral Bioavailability, Anti-Tumor Activity and Hepatoprotective Effect of 6-Shogaol Loaded in a Type of Novel Micelles of Polyethylene Glycol and Linoleic Acid Conjugate.Pharmaceutics · 2019Article
- Review
- Brush-First and ROMP-Out with Functional (Macro)monomers: Method Development, Structural Investigations, and Applications of an Expanded Brush-Arm Star Polymer Platform.Macromolecules · 2018Article
- Triply Loaded Nitroxide Brush-Arm Star Polymers Enable Metal-Free Millimetric Tumor Detection by Magnetic Resonance Imaging.ACS nano · 2018Article
- A Vinyl Ether-Functional Polycarbonate as a Template for Multiple Postpolymerization Modifications.Macromolecules · 2018Article
- Scalable Synthesis of Multivalent Macromonomers for ROMP.ACS macro letters · 2018Article
- Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer-Assisted Compaction.Small (Weinheim an der Bergstrasse, Germany) · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when employed in conjunction with a poly(ethylene glycol) (PEG) macromonomer, provided highly controlled BASP formation reactions. A combination of this new cross-linker with a novel doxorubicin (DOX)-
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.