ArticleInternational journal of systematic and evolutionary microbiology2014
Brucella papionis sp. nov., isolated from baboons (Papio spp.).
Article in International journal of systematic and evolutionary microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 2 of them syntheses that pooled it.
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Who cites it
96 citing papers in PubMed, 2 syntheses or guidelines pooled it, 214 citations in OpenAlex.
- Brucellosis in wildlife in Africa: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection.BMC public health · 2016Pooled it
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- Epidemiological baseline of Brucella spp. in South African wildlife.PLoS neglected tropical diseases · 2025Article
- Brucellosis in the omics era: integrative perspectives on Brucella genomic architecture, host-pathogen interactions, and disease dynamics.World journal of microbiology & biotechnology · 2025Review
- Investigation of genomic island 2 deciphers the evolution of a genus Brucella.Scientific reports · 2025Article
- Brucella microti and Rodent-Borne Brucellosis: A Neglected Public Health Threat.Zoonoses and public health · 2025Review
- Animal Brucellosis in Egypt: Review on Evolution, Epidemiological Situation, PrevalentMicroorganisms · 2025Review
- Complete genome assembly and functional characterization ofFrontiers in cellular and infection microbiology · 2025Article
- Molecular typing methods to characterizeVeterinary world · 2024Review
- A recombinase polymerase amplification-SYBR Green I assay for the rapid and visual detection of Brucella.Folia microbiologica · 2024Article
- Rapid Identification ofMicroorganisms · 2024Article
- Ochrobactrum chromiisoli sp. nov., Isolated from Chromium-Contaminated Soil.Current microbiology · 2023Article
- Cell and Tissue Tropism of Brucella spp.Infection and immunity · 2023Review
- Hepatobiliary Brucellosis: Brucella Bacteremia Presenting with Refractory Hepatobiliary Infection.Case reports in critical care · 2023Article
- Antigenic and molecular evidence ofFrontiers in veterinary science · 2023Article
- Isolation ofFrontiers in microbiology · 2023Article
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- Brucellosis in the Brazilian Pantanal wetland: threat to animal production and wildlife conservation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
36 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 9 institutions in 4 countries.
Funding
Abstract
Two Gram-negative, non-motile, non-spore-forming coccoid bacteria (strains F8/08-60(T) and F8/08-61) isolated from clinical specimens obtained from baboons (Papio spp.) that had delivered stillborn offspring were subjected to a polyphasic taxonomic study. On the basis of 16S rRNA gene sequence similarities, both strains, which possessed identical sequences, were assigned to the genus Brucella. This placement was confirmed by extended multilocus sequence analysis (MLSA), where both strains possessed identical sequences, and whole-genome sequencing of a representative isolate. All of the above analyses suggested that the two strains represent a novel lineage within the genus Brucella. The strains also possessed a unique profile when subjected to the phenotyping approach classically used to separate species of the genus Brucella, reacting only with Brucella A monospecific antiserum, being sensitive to the dyes thionin and fuchsin, being lysed by bacteriophage Wb, Bk2 and Fi phage at routine test dilution (RTD) but only partially sensitive to bacteriophage Tb, and with no requirement for CO2 and no production of H2S but strong urease activity. Biochemical profiling revealed a pattern of enzyme activity and metabolic capabilities distinct from existing species of the genus Brucella. Molecular analysis of the omp2 locus genes showed that both strains had a novel combination of two highly similar omp2b gene copies. The two strains shared a unique fingerprint profile of the multiple-copy Brucella-specific element IS711. Like MLSA, a multilocus variable number of tandem repeat analysis (MLVA) showed that the isolates clustered together very closely, but represent a distinct group within the genus Brucella. Isolates F8/08-60(T) and F8/08-61 could be distinguished clearly from all known species of the genus Brucella and their biovars by both phenotypic and molecular properties. Therefore, by applying the species concept for the genus Brucella suggested by the ICSP Subcommittee on the Taxonomy of Brucella, they represent a novel species within the genus Brucella, for which the name Brucella papionis sp. nov. is proposed, with the type strain F8/08-60(T) ( = NCTC 13660(T) = CIRMBP 0958(T)).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.