Evidence map›Paper›PMID 25241756›Full record

Trial reportActa neuropsychiatrica2014

Protocol to evaluate the impact of yoga supplementation on cognitive function in schizophrenia: a randomised controlled trial.

Triptish Bhatia, Sati Mazumdar, Nagendra Narayan Mishra, Raquel E Gur, Ruben C Gur, Vishwajit Laxmikant Nimgaonkar, Smita Neelkanth Deshpande

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Acta neuropsychiatrica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Yoga as part of a package of care versus standard care for schizophrenia.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Yoga versus non-standard care for schizophrenia.The Cochrane database of systematic reviews · 2017
    Pooled it
  4. Yoga versus standard care for schizophrenia.The Cochrane database of systematic reviews · 2015
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Triptish Bhatia1Department of Psychiatry,Post-Graduate Institute of Medical Education and Research - Dr. Ram Manohar Lohia Hospital,New Delhi,India.
Sati Mazumdar2Department of Biostatistics,University of Pittsburgh,Pittsburgh,PA,USA.
Nagendra Narayan Mishra1Department of Psychiatry,Post-Graduate Institute of Medical Education and Research - Dr. Ram Manohar Lohia Hospital,New Delhi,India.
Raquel E Gur3Department of Psychiatry,University of Pennsylvania,Philadelphia,PA,USA.
Ruben C Gur3Department of Psychiatry,University of Pennsylvania,Philadelphia,PA,USA.
Vishwajit Laxmikant Nimgaonkar4Department of Psychiatry,University of Pittsburgh,Pittsburgh,PA,USA.
Smita Neelkanth Deshpande1Department of Psychiatry,Post-Graduate Institute of Medical Education and Research - Dr. Ram Manohar Lohia Hospital,New Delhi,India.
Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · INUniversity of Pennsylvania · USUniversity of Pittsburgh · US

Funding

Tri National Training Program in Psychiatric GeneticsD43TW008302 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MANSOUR, HADER A., NIMGAONKAR, VISHWAJIT LAXMIKANT · 2009 to 2013
$542k
The Impact of Yoga Supplementation On Cognitive Function Among Indian OutpatientsR01TW008289 · FIC · DR RAM MANOHAR LOHIA HOSPITAL · PI BHATIA, TRIPTISH · 2010 to 2014
$264k
FIC NIH HHS D43 TW008302FIC NIH HHS R01 TW008289FIC NIH HHS TW008289FIC NIH HHS TW008302
6 · The paper itself

Abstract

backgroundSchizophrenia (SZ) is a chronic illness that is treated symptomatically. Cognitive dysfunction is a core feature of SZ that is relatively intractable to pharmacotherapy. Yoga can improve cognitive function among healthy individuals. A recent open trial indicated significant benefits of yoga training (YT) in conjunction with conventional pharmacotherapy among patients with SZ.

aimsTo describe the protocol for an ongoing randomised controlled trial designed to test whether the reported beneficial effects of YT on cognitive function among SZ patients can be replicated. Secondarily, the effects of YT on daily functioning living skills are evaluated.

methodsConsenting patients with SZ receive routine clinical treatment and are randomised to adjunctive YT, adjunctive physical exercise (PE) or treatment as usual (proposed N = 234 total, N = 78 in each group). The trial involves YT or PE 5 days a week and lasts 3 weeks. Participants are evaluated thrice over 6 months. Cognitive functions measured by Trail Making Test, University of Pennsylvania Neurocognitive Computerised Battery were primary outcome measures while clinical severity and daily functioning measured by Independent Living Skills Survey were secondary outcome measures.

resultsA total of 309 participants have been randomised as of 31 August 2013, which exceeded beyond 294 proposed after attrition. Once participants begin YT or PE they generally complete the protocol. No injuries have been reported.

conclusionsShort term YT is feasible and acceptable to Indian SZ patients. If beneficial effects of YT are detected, it will provide a novel adjunctive cognitive remediation strategy for SZ patients.

Indexed as

Exercise TherapyYogaCognitionHumansIndependent LivingSchizophreniaSingle-Blind MethodSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID25241756
PMCPMC4342363
OpenAlexW2153565734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.