Evidence map›Paper›PMID 25241387›Full record

ArticleResearch in veterinary science2014

Relationship between rate of infection and markers of inflammation/immunity in Holy Birman cats with feline coronavirus.

S Paltrinieri, G Rossi, A Giordano

Abstract readComparative Study
In one paragraph

Article in Research in veterinary science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S PaltrinieriDepartment of Veterinary Sciences and Public Health, University of Milan, Via Celoria 10, 20133, Milan, Italy. Electronic address: saverio.paltrinieri@unimi.it.
G RossiDepartment of Veterinary Sciences and Public Health, University of Milan, Via Celoria 10, 20133, Milan, Italy.
A GiordanoDepartment of Veterinary Sciences and Public Health, University of Milan, Via Celoria 10, 20133, Milan, Italy.
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess whether Holy Birman cats (HB) have a peculiar immune profile and a higher rate of infection by feline coronaviruses (FCoV). Leucocyte and lymphocyte subsets, antibody titers, α1-acid glycoprotein (AGP), globulin fractions, IL-4, IL-12 and IFN-γ in blood and fecal FCoV excretion were determined in HB (n = 75) and in cats from other breeds (n = 94). Significantly higher CD4/CD8 ratio, IFN-γ concentration and IL12/IL4 ratio and significantly lower IL-4 concentration and proportion of shedders were found in HB than in other breeds. No other differences were found. In conclusion, this study did not provide evidence of peculiar immune profiles in HB, except for a prevalent Th1 profile, that may explain why in our caseload the rate of shedders was lower in HB than in other breeds.

Indexed as

Coronavirus, FelineAnimalsAntibodies, ViralBiomarkersCatsCD4-CD8 RatioFeline Infectious PeritonitisImmunity, InnateInflammationInterleukin-12Interleukin-4LeukocytesLymphocyte SubsetsMaleOrosomucoidPrevalenceAntibodies, ViralBiomarkersInterleukin-12Interleukin-4OrosomucoidCD4/CD8 ratioFeline coronavirus (FCoV)Feline infectious peritonitis (FIP)Holy Birman catTh1 cytokinesα(1)-acid glycoprotein (AGP)

Identifiers

PMID25241387
PMCPMC7111858
OpenAlexW1999924260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.