Evidence map›Paper›PMID 25241232›Full record

SynthesisThe Lancet. Infectious diseases2014

The global burden of listeriosis: a systematic review and meta-analysis.

Charline Maertens de Noordhout, Brecht Devleesschauwer, Frederick J Angulo, Geert Verbeke, Juanita Haagsma, Martyn Kirk, Arie Havelaar, Niko Speybroeck

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Lancet. Infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 262 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
262citing papers in PubMed, 1 pooled it
45.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

262 citing papers in PubMed, 1 synthesis or guideline pooled it, 618 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Persistence ofFrontiers in microbiology · 2026
    Review
  16. Microorganisms · 2025
    Review
  17. Exploring the prevalence and antibiotic resistance of Listeria monocytogenes in diverse food commodities across Sikkim, India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  18. Article
  19. Article
  20. One health (Amsterdam, Netherlands) · 2025
    Review

202 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Charline Maertens de Noordhout *Institute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Brecht Devleesschauwer *Institute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Frederick J AnguloInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Geert VerbekeInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Juanita HaagsmaInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Martyn KirkInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Arie HavelaarInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
Niko SpeybroeckInstitute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium (C Maertens de Noordhout MSc, B Devleesschauwer MSc, Prof N Speybroeck PhD); Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium (B Devleesschauwer); Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA (F J Angulo PhD); Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Leuven, Belgium (Prof G Verbeke PhD); Department of Public Health, Erasmus MC, Rotterdam, Netherlands (J Haagsma PhD); National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia (M Kirk PhD); National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, Netherlands (Prof A Havelaar PhD); and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands (Prof A Havelaar).
UCLouvain · BEGhent University · BE

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundListeriosis, caused by Listeria monocytogenes, is an important foodborne disease that can be difficult to control and commonly results in severe clinical outcomes. We aimed to provide the first estimates of global numbers of illnesses, deaths, and disability-adjusted life-years (DALYs) due to listeriosis, by synthesising information and knowledge through a systematic review.

methodsWe retrieved data on listeriosis through a systematic review of peer-reviewed and grey literature (published in 1990-2012). We excluded incidence data from before 1990 from the analysis. We reviewed national surveillance data where available. We did a multilevel meta-analysis to impute missing country-specific listeriosis incidence rates. We used a meta-regression to calculate the proportions of health states, and a Monte Carlo simulation to generate DALYs by WHO subregion.

findingsWe screened 11,722 references and identified 87 eligible studies containing listeriosis data for inclusion in the meta-analyses. We estimated that, in 2010, listeriosis resulted in 23,150 illnesses (95% credible interval 6061-91,247), 5463 deaths (1401-21,497), and 172,823 DALYs (44,079-676,465). The proportion of perinatal cases was 20·7% (SD 1·7).

interpretationOur quantification of the global burden of listeriosis will enable international prioritisation exercises. The number of DALYs due to listeriosis was lower than those due to congenital toxoplasmosis but accords with those due to echinococcosis. Urgent efforts are needed to fill the missing data in developing countries. We were unable to identify incidence data for the AFRO, EMRO, and SEARO WHO regions.

fundingWHO Foodborne Diseases Epidemiology Reference Group and the Université catholique de Louvain.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleFoodborne DiseasesGlobal HealthHumansIncidenceInfantListeria monocytogenesListeriosisMaleMiddle Aged

Identifiers

PMID25241232
PMCPMC4369580
OpenAlexW2097006899

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.