ArticleNanomedicine : nanotechnology, biology, and medicine2015
Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent.
Article in Nanomedicine : nanotechnology, biology, and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 1 synthesis or guideline pooled it, 495 citations in OpenAlex.
- The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review.Mini reviews in medicinal chemistry · 2024Pooled it
- Advanced antibacterial wound management: comparative study of non-antibiotic drug elution and nanoparticle integration.International journal of pharmaceutics: X · 2026Article
- Surface charge-dependent effects of BSA-curcumin nanoparticles combined with amikacin in antimicrobial photodynamic therapy: A pilot In Vivo study of multidrug-resistant Pseudomonas aeruginosa skin infection.Lasers in medical science · 2026Article
- Design and Characterization of a Bioinspired PAMAM@Poly(Caffeic Acid) Magnetite Nanocarrier for Curcumin Delivery.ACS omega · 2026Article
- Turmeric Polymer Fiber Mats (T-PFMs): Solution Blow Spun Turmeric/PLGA Composites as a Comprehensive Wound Care Platform.ACS applied polymer materials · 2026Article
- The Effect of Free and Nanoliposomal Curcumin on the Viability and Acid Production of Single-Species (Streptococcus mutans) and Polymicrobial Biofilms.Clinical and experimental dental research · 2026Article
- Chitosan-Nanoencapsulated Curcumin for the Treatment of Diabetic Foot Ulcers: A Review.Polymers · 2026Review
- Curcumin-berberine ointment based on multifunctional carrier accelerates wound healing in a translational porcine model of tail-biting injuries: a controlled study against oxytetracycline.Frontiers in pharmacology · 2026Article
- Nanocarrier-integrated multilayer films produced by 3D printing for improved skin adhesion and curcumin photostability.Beilstein journal of nanotechnology · 2026Article
- Synergistic effects of herbal extracts and nanoparticles in skin damage repair: A comprehensive review.Avicenna journal of phytomedicine · 2026Review
- Therapeutic Potential of Chitosan-Based and Related Nanocomposite Systems in Wound Management: A Review.International journal of molecular sciences · 2025Review
- Liposome integrated hydrogel for diabetic wound healing: molecular mechanisms in inflammation and oxidative stress mitigation.Inflammopharmacology · 2025Article
- Curcumin-Functionalized Ag and ZnO Nanoparticles: A Nanotherapeutic Approach for Treating Infections in Diabetic Wounds.Bioengineering (Basel, Switzerland) · 2025Article
- Biosynthesized Silver Nanoparticles Modulate Inflammation in a Palatine Wound Model.Clinical and experimental dental research · 2025Article
- Curcumin and Papain-Loaded Liposomal Natural Latex Dressings with Phototherapy: A Synergistic Approach to Diabetic Wound Healing.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Newly designed curcumin-loaded hybrid nanoparticles: a multifunctional strategy for combating oxidative stress, inflammation, and infections to accelerate wound healing and tissue regeneration.BMC biotechnology · 2025Article
- A Natural Latex-Based Smart Dressing for Curcumin Delivery Combined with LED Phototherapy in Diabetic Foot Ulcers: A Pilot Clinical Study.Pharmaceutics · 2025Article
- Review of the 100 Most Cited Articles inEuropean burn journal · 2025Review
- Modulating Polyphenol Activity with Metal Ions: Insights into Dermatological Applications.Pharmaceutics · 2025Review
65 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
Burn wounds are often complicated by bacterial infection, contributing to morbidity and mortality. Agents commonly used to treat burn wound infection are limited by toxicity, incomplete microbial coverage, inadequate penetration, and rising resistance. Curcumin is a naturally derived substance with innate antimicrobial and wound healing properties. Acting by multiple mechanisms, curcumin is less likely than current antibiotics to select for resistant bacteria. Curcumin's poor aqueous solubility and rapid degradation profile hinder usage; nanoparticle encapsulation overcomes this pitfall and enables extended topical delivery of curcumin. In this study, we synthesized and characterized curcumin nanoparticles (curc-np), which inhibited in vitro growth of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa in dose-dependent fashion, and inhibited MRSA growth and enhanced wound healing in an in vivo murine wound model. Curc-np may represent a novel topical antimicrobial and wound healing adjuvant for infected burn wounds and other cutaneous injuries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.