ReviewCurrent osteoporosis reports2014
Vibrational spectroscopic imaging for the evaluation of matrix and mineral chemistry.
Review in Current osteoporosis reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 75 citations in OpenAlex.
- Cortical bone material / compositional changes in children with mild osteogenesis imperfecta.Bone reports · 2026Article
- Effects of different numbers of micro-osteoperforations on acceleration of orthodontic tooth movement and alveolar bone remodeling in rats.BMC oral health · 2026Article
- Fourier Transform Infrared Imaging of Bone.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Article
- Utilizing surface-enhanced Raman spectroscopy for the adjunctive diagnosis of osteoporosis.European journal of medical research · 2024Article
- Long-Term Fate and Efficacy of a Biomimetic (Sr)-Apatite-Coated Carbon Patch Used for Bone Reconstruction.Journal of functional biomaterials · 2023Article
- The extracellular matrix of human bone marrow adipocytes and glucose concentration differentially alter mineralization quality without impairing osteoblastogenesis.Bone reports · 2022Article
- Material and nanomechanical properties of bone structural units of cortical and trabecular iliac bone tissues from untreated postmenopausal osteoporotic women.Bone reports · 2022Article
- Chronological Age Estimation of Male Occipital Bone Based on FTIR and Raman Microspectroscopy.Bioinorganic chemistry and applications · 2022Article
- Nothobranchius furzeri, the Turquoise Killifish: A Model of Age-Related Osteoporosis?Gerontology · 2022Article
- Mechano-chemistry of human femoral diaphysis revealed by correlative Brillouin-Raman microspectroscopy.Scientific reports · 2020Article
- Investigation of changes in bone density and chemical composition associated with bone marrow oedema-type appearances in magnetic resonance images of the equine forelimb.BMC musculoskeletal disorders · 2019Article
- Multiscale analyses reveal native-like lamellar bone repair and near perfect bone-contact with porous strontium-loaded bioactive glass.Biomaterials · 2019Article
- Narrowband-autofluorescence imaging for bone analysis.Biomedical optics express · 2019Article
- Characterization of the Biological Fingerprint and Identification of Associated Parameters in Stress Fractures by FTIR Spectroscopy.BioMed research international · 2019Article
- Effect of osteoporosis treatment agents on the cortical bone osteocyte microenvironment in adult estrogen-deficient, osteopenic rats.Bone reports · 2018Article
- Raman spectroscopic imaging for quantification of depth-dependent and local heterogeneities in native and engineered cartilage.NPJ Regenerative medicine · 2018Article
- Bone quality changes associated with aging and disease: a review.Annals of the New York Academy of Sciences · 2017Review
- Applying Full Spectrum Analysis to a Raman Spectroscopic Assessment of Fracture Toughness of Human Cortical Bone.Applied spectroscopy · 2017Article
- Vibrational spectroscopic techniques to assess bone quality.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Metabolic bone diseases manifesting fragility fractures (such as osteoporosis) are routinely diagnosed based on bone mineral density (BMD) measurements, and the effect of various therapies also evaluated based on the same outcome. Although useful, it is well recognized that this metric does not fully account for either fracture incidence or the effect of various therapies on fracture incidence, thus, the emergence of bone quality as a contributing factor in the determination of bone strength. Infrared and Raman vibrational spectroscopic techniques are particularly well-suited for the determination of bone quality as they provide quantitative and qualitative information of the mineral and organic matrix bone components, simultaneously. Through the use of microspectroscopic techniques, this information is available in a spatially resolved manner, thus, the outcomes may be easily correlated with outcomes from techniques such as histology, histomorphometry, and nanoindentation, linking metabolic status with material properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.