ArticleNeuroinformatics2015
NeuroMorph: a toolset for the morphometric analysis and visualization of 3D models derived from electron microscopy image stacks.
Article in Neuroinformatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Ultrastructure of astrocytes using volume electron microscopy: A scoping review.The Journal of physiology · 2026Article
- ToPoMesh: accurate 3D surface reconstruction from CT volumetric data via topology modification.Medical & biological engineering & computing · 2025Article
- An analysis of contractile and protrusive cell behaviors at the superficial surface of the zebrafish neural plate.Developmental dynamics : an official publication of the American Association of Anatomists · 2025Article
- AI-powered automated model construction for patient-specific CFD simulations of aortic flows.Science advances · 2025Article
- Physical structure of the environment contributes to the development of diversity of microalgal assemblages.Scientific reports · 2024Article
- Modular segmentation, spatial analysis and visualization of volume electron microscopy datasets.Nature protocols · 2024Review
- Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal.Nature cell biology · 2024Article
- Article
- Fossil brains provide evidence of underwater feeding in early seals.Communications biology · 2023Article
- CellRemorph: A Toolkit for Transforming, Selecting, and Slicing 3D Cell Structures on the Road to Morphologically Detailed Astrocyte Simulations.Neuroinformatics · 2023Article
- Multi-synaptic boutons are a feature of CA1 hippocampal connections in the stratum oriens.Cell reports · 2023Article
- IMAGE-IN: Interactive web-based multidimensional 3D visualizer for multi-modal microscopy images.PloS one · 2022Article
- Resolving physical interactions between bacteria and nanotopographies with focused ion beam scanning electron microscopy.iScience · 2021Article
- Ultrastructural analysis of dendritic spine necks reveals a continuum of spine morphologies.Developmental neurobiology · 2021Article
- Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation.eLife · 2020Article
- Connexin43 expression in bone marrow derived cells contributes to the electrophysiological properties of cardiac scar tissue.Scientific reports · 2020Article
- The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.Molecular cell · 2019Article
- Ultrastructural basis of strong unitary inhibition in a binaural neuron.The Journal of physiology · 2018Article
- A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration.Neuron · 2018Article
- NeuroMorphoVis: a collaborative framework for analysis and visualization of neuronal morphology skeletons reconstructed from microscopy stacks.Bioinformatics (Oxford, England) · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serialelectron microscopy imaging is crucial for exploring the structure of cells and tissues. The development of block face scanning electron microscopy methods and their ability to capture large image stacks, some with near isotropic voxels, is proving particularly useful for the exploration of brain tissue. This has led to the creation of numerous algorithms and software for segmenting out different features from the image stacks. However, there are few tools available to view these results and make detailed morphometric analyses on all, or part, of these 3D models. We have addressed this issue by constructing a collection of software tools, called NeuroMorph, with which users can view the segmentation results, in conjunction with the original image stack, manipulate these objects in 3D, and make measurements of any region. This approach to collecting morphometric data provides a faster means of analysing the geometry of structures, such as dendritic spines and axonal boutons. This bridges the gap that currently exists between rapid reconstruction techniques, offered by computer vision research, and the need to collect measurements of shape and form from segmented structures that is currently done using manual segmentation methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.