Evidence map›Paper›PMID 25240151›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2014

Rapid-scan EPR of immobilized nitroxides.

Zhelin Yu, Richard W Quine, George A Rinard, Mark Tseitlin, Hanan Elajaili, Velavan Kathirvelu, Laura J Clouston, Przemysław J Boratyński, Andrzej Rajca, Richard Stein and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Advances in rapid scan EPR spectroscopy.Methods in enzymology · 2022
    Article
  2. Review
  3. EPR Everywhere.Applied magnetic resonance · 2021
    Review
  4. Article
  5. Article
  6. Full cycle rapid scan EPR deconvolution algorithm.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017
    Article
  7. Rapid-scan EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017
    Review
  8. Article
  9. Article
  10. Article
  11. Field-stepped direct detection electron paramagnetic resonance.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2015
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Zhelin YuDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Richard W QuineSchool of Engineering and Computer Science, University of Denver, Denver, CO 80208, USA.
George A RinardSchool of Engineering and Computer Science, University of Denver, Denver, CO 80208, USA.
Mark TseitlinDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Hanan ElajailiDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Velavan KathirveluDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Laura J CloustonDepartment of Chemistry, University of Nebraska, Lincoln, NE 68588-0304, USA.
Przemysław J BoratyńskiDepartment of Chemistry, University of Nebraska, Lincoln, NE 68588-0304, USA.
Andrzej RajcaDepartment of Chemistry, University of Nebraska, Lincoln, NE 68588-0304, USA.
Richard SteinDepartment of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Hassane MchaourabDepartment of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Sandra S EatonDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Gareth R EatonDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA. Electronic address: geaton@du.edu.
University of Denver · USUniversity of Nebraska–Lincoln · USVanderbilt University Medical Center · US

Funding

Rapid Scan Biomedical EPR Spectroscopy and ImagingR01EB000557 · NIBIB · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI EATON, GARETH R · 2002 to 2011
$4.0M
Rapid Scan Biomedical EPR Spectroscopy and ImagingR56EB000557 · NIBIB · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI EATON, GARETH R · 2007 to 2007
$494k
Enhancing in vivo EPR imaging using spin probes with short relaxation timesK25EB016040 · NIBIB · WEST VIRGINIA UNIVERSITY · PI TSEYTLIN, MARK · 2013 to 2015
$416k
Midwest Center for Membrane Protein Structural DynamicsR24GM084757 · NIGMS · UNIVERSITY OF CHICAGO · PI PEROZO, EDUARDO A · 2008 to 2008
$77k
NIBIB NIH HHS EB000557NIBIB NIH HHS K25 EB016040NIBIB NIH HHS R01 EB000557NIBIB NIH HHS R56 EB000557NIGMS NIH HHS R24 GM084757NIGMS NIH HHS U54 GM084757
6 · The paper itself

Abstract

X-band electron paramagnetic resonance spectra of immobilized nitroxides were obtained by rapid scan at 293 K. Scan widths were 155 G with 13.4 kHz scan frequency for (14)N-perdeuterated tempone and for T4 lysozyme doubly spin labeled with an iodoacetamide spirocyclohexyl nitroxide and 100 G with 20.9 kHz scan frequency for (15)N-perdeuterated tempone. These wide scans were made possible by modifications to our rapid-scan driver, scan coils made of Litz wire, and the placement of highly conducting aluminum plates on the poles of a Bruker 10″ magnet to reduce resistive losses in the magnet pole faces. For the same data acquisition time, the signal-to-noise for the rapid-scan absorption spectra was about an order of magnitude higher than for continuous wave first-derivative spectra recorded with modulation amplitudes that do not broaden the lineshapes.

Indexed as

DeuteriumElectromagnetic FieldsElectron Spin Resonance SpectroscopyIndicators and ReagentsMuramidaseNitrogen OxidesNitrogen RadioisotopesSpin LabelsTriacetoneamine-N-OxylDeuteriumIndicators and ReagentsMuramidaseNitrogen OxidesNitrogen RadioisotopesSpin LabelsTriacetoneamine-N-OxylImmobilized nitroxideLitz wire coilsRapid scan EPRSucrose octaacetate glassTrehalose glass

Identifiers

PMID25240151
PMCPMC4247172
OpenAlexW2041547322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.