Evidence map›Paper›PMID 25240070›Full record

Trial reportThe American journal of clinical nutrition2014

Targeted prevention of excess weight gain and eating disorders in high-risk adolescent girls: a randomized controlled trial.

Marian Tanofsky-Kraff, Lauren B Shomaker, Denise E Wilfley, Jami F Young, Tracy Sbrocco, Mark Stephens, Lisa M Ranzenhofer, Camden Elliott, Sheila Brady, Rachel M Radin and 8 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00680979 phase2completednot on this map

Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity

TypeinterventionalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2008 to 2015Enrolled166ConditionsObesity, Overweight, Binge EatingArmsInterpersonal Psychotherapy, Health Education
NCT02745795 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Motivational Intervention Through the Generation of an Interpersonal Plan About Nutrition and Physical Exercise Study (IMAGINE Study), a Randomized Controlled Trial With Obese and Overweight Adolescents in Portuguese High Schools

TypeinterventionalSponsorCentro Hospitalar Lisboa NorteRan2015 to 2016Enrolled83ConditionsObesityArmsMotivational Interview, Conventional Interview
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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  16. A Randomized Controlled Trial to Prevent Depression and Ameliorate Insulin Resistance in Adolescent Girls at Risk for Type 2 Diabetes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Marian Tanofsky-KraffFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Lauren B ShomakerFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Denise E WilfleyFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Jami F YoungFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Tracy SbroccoFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Mark StephensFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Lisa M RanzenhoferFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Camden ElliottFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Sheila BradyFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Rachel M RadinFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Anna VannucciFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Edny J BryantFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Robyn OsbornFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Sarah S BergerFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Cara OlsenFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Merel KozloskyFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
James C ReynoldsFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
Jack A YanovskiFrom Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD (MT-K, LBS, TS, MS, LMR, CE, RMR, AV, EJB, RO, SSB, and CO); the Nutrition Department (MK) and Nuclear Medicine Department (JCR), Hatfield Clinical Research Center, and the Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (MT-K, LBS, LMR, CE, SB, RMR, AV, SSB, and JAY), NIH, Bethesda, MD; the Department of Psychiatry, Washington University School of Medicine, St Louis, MO (DEW); and Applied and Professional Psychology, Rutgers University, Piscataway Township, NJ (JFY).
National Institutes of Health · USUniformed Services University of the Health Sciences · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USRutgers, The State University of New Jersey · USWashington University in St. Louis · US

Funding

Physiology, Psychology, and Genetics of ObesityZIAHD000641 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YANOVSKI, JACK A. · 2009 to 2025
$24.8M
Preventing excessive weight gain in adolescent girls at high-risk for adult obesiR01DK080906 · NIDDK · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI TANOFSKY-KRAFF, MARIAN · 2008 to 2011
$1.4M
Clinical Research in Eating Disorders and ObesityK24MH070446 · NIMH · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 2004 to 2013
$1.4M
Intramural NIH HHSNHLBI NIH HHS ZIA-HO-00641NIDDK NIH HHS 1R01DK080906NIMH NIH HHS 1K24 MH070446
6 · The paper itself

Abstract

backgroundThe high prevalence and incidence of obesity and eating disorders in US adolescent girls are serious health problems. Because of the shared risk factors for obesity and eating disorders, a targeted prevention of both conditions is a priority.

objectiveWe determined whether an adapted interpersonal psychotherapy prevention program is more efficacious for reducing excess weight gain and worsening disordered eating than health education in adolescent girls at high risk of obesity and eating disorders.

designA parallel-group, randomized controlled trial was conducted between September 2008 and January 2013 in a university-based laboratory and a federal research hospital. The study included 113 adolescent (12-17-y-old) girls deemed at high risk of adult obesity and eating disorders because of a body mass index (BMI) between the 75th and 97th percentiles and reports of episodes of a loss of control over their eating. Girls were randomly assigned to participate in an adapted interpersonal psychotherapy or a health-education group program for 12 weekly 90-min group sessions. Follow-up assessments occurred immediately after group programs and at 6 and 12 mo.

resultsParticipation in both conditions was associated with decreases in expected BMI gain, age-adjusted BMI metrics, the percentage of fat by using dual-energy X-ray absorptiometry, symptoms of depression and anxiety, and the frequency of loss-of-control eating over 12 mo of follow-up (Ps < 0.001) with no group difference. In follow-up analyses, interpersonal psychotherapy was more efficacious than health education at reducing objective binge eating at the 12-mo follow-up (P < 0.05).

conclusionsThe intervention with adolescent girls with loss-of-control eating is associated with lower age-adjusted BMI and percentage of adiposity as well as improved mood symptoms over 1 y. Interpersonal psychotherapy further reduced objective binge eating. Additional research is needed to elucidate the mechanisms by which physical and psychological improvements were observed. This trial was registered at clinicaltrials.gov as NCT00680979.

Indexed as

Weight GainAbsorptiometry, PhotonAdiposityAdolescentBinge-Eating DisorderBody Mass IndexChildFemaleFollow-Up StudiesHealth BehaviorHealth EducationHumansObesityProspective StudiesPsychotherapyRisk Factors

Identifiers

PMID25240070
PMCPMC4163791
OpenAlexW2068104694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.