ArticleGene2014
Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex.
Article in Gene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Molecular Identification ofBiology · 2026Article
- Epigenetic and Gene Expression Responses ofMolecules (Basel, Switzerland) · 2025Article
- Thyroid-like hormone signaling in invertebrates and its potential role in initial screening of thyroid hormone system disrupting chemicals.Integrated environmental assessment and management · 2023Review
- The reproductive effects of the cancer chemotherapy agent, Carmofur, on Daphnia magna are mediated by its metabolite, 5-Fluorouracil.Ecotoxicology (London, England) · 2022Article
- 17β-Estradiol (E2) may be involved in the mode of crustacean female sex hormone (CFSH) action in the blue crab,Frontiers in endocrinology · 2022Article
- Expression variations of two retinoid signaling pathway receptors in the rotifer Brachionus calyciflorus exposed to three endocrine disruptors.Ecotoxicology (London, England) · 2021Article
- Article
- Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Step in Protection from Xenobiotics.Nuclear receptor research · 2019Article
- Article
- Article
- Annotation of the Nuclear Receptors in an Estuarine Fish species,Nuclear receptor research · 2017Article
- Mechanisms of Action of Compounds That Enhance Storage Lipid Accumulation in Daphnia magna.Environmental science & technology · 2016Article
- Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturated fatty acids or environmental toxicants in Daphnia magna.Chemosphere · 2016Article
- The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA.Chemosphere · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Most nuclear receptors (NRs) are ligand-dependent transcription factors crucial in homeostatic physiological responses or environmental responses. We annotated the Daphnia magna NRs and compared them to Daphnia pulex and other species, primarily through phylogenetic analysis. Daphnia species contain 26 NRs spanning all seven gene subfamilies. Thirteen of the 26 receptors found in Daphnia species phylogenetically segregate into the NR1 subfamily, primarily involved in energy metabolism and resource allocation. Some of the Daphnia NRs, such as RXR, HR96, and E75 show strong conservation between D. magna and D. pulex. Other receptors, such as EcRb, THRL-11 and RARL-10 have diverged considerably and therefore may show different functions in the two species. Curiously, there is an inverse association between the number of NR splice variants and conservation of the LBD. Overall, D. pulex and D. magna possess the same NRs; however not all of the NRs demonstrate high conservation indicating the potential for a divergence of function.
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Registered trials
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