ReviewSeminars in perinatology2014
Apnea in acute bilirubin encephalopathy.
Review in Seminars in perinatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Computer-aided diagnosis of neonatal acute bilirubin encephalopathy with multi-modal MRI images and convolutional neural networks.Scientific reports · 2026Article
- Unbound bilirubin and risk of severe neurodevelopmental impairment in extremely low birthweight newborns.Pediatric research · 2025Article
- Detecting acute bilirubin encephalopathy in neonates based on multimodal MRI with deep learning.Pediatric research · 2022Article
- Magnetic Resonance Image of Neonatal Acute Bilirubin Encephalopathy: A Diffusion Kurtosis Imaging Study.Frontiers in neurology · 2021Article
- Clinicopathological Spectrum of Bilirubin Encephalopathy/Kernicterus.Diagnostics (Basel, Switzerland) · 2019Review
- Prevalence and burden of illness of treated hemolytic neonatal hyperbilirubinemia in a privately insured population in the United States.BMC pediatrics · 2019Article
- Influence of Moderate Hyperbilirubinemia on Cardiorespiratory Control in Preterm Lambs.Frontiers in physiology · 2019Article
- Bilirubin Binding Capacity in the Preterm Neonate.Clinics in perinatology · 2016Review
- Moderate Hyperbilirubinemia Alters Neonatal Cardiorespiratory Control and Induces Inflammation in the Nucleus Tractus Solitarius.Frontiers in physiology · 2016Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Central apnea, defined as cessation of breathing for ≥20s, is frequent in premature infants born at <34 weeks׳ gestation but uncommon among healthy late preterm (34(0/7)-36(6/7) weeks׳ gestation) and term (≥37 weeks׳ gestation) infants, where it is usually a clinical manifestation of a neurological or metabolic problem. There is growing evidence that marked unconjugated hyperbilirubinemia is associated with central apnea in neonates. This article explores the reported association between acute bilirubin encephalopathy and symptomatic apneic events in newborns and the possible mechanisms involved in the pathogenesis of this phenomenon. The prevalence of symptomatic apneic events in reports of acute bilirubin encephalopathy suggests this clinical finding should be considered a sign of bilirubin neurotoxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.