Evidence map›Paper›PMID 25239389›Full record

ArticleJournal of neurology2014

Assessment of patients with disorder of consciousness: do different Coma Recovery Scale scoring correlate with different settings?

Davide Sattin, Ambra M Giovannetti, Francesca Ciaraffa, Venusia Covelli, Anna Bersano, Anna Nigri, Stefania Ferraro, Ludovico Minati, Davide Rossi, Dunja Duran and 2 more

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Article in Journal of neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

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  4. The social and family evaluation (SAFE) scale for caregivers of individuals with disorders of consciousness: preliminary results.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  8. Behavioral scales variability in patients with prolonged disorders of consciousness.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Davide SattinNeurology Public Health and Disability Unit, Scientific Directorate, Neurological Institute C. Besta IRCCS Foundation, Via Celoria 11, Milan, 20133, Italy, davide.sattin@istituto-besta.it.
Ambra M Giovannetti
Francesca Ciaraffa
Venusia Covelli
Anna Bersano
Anna Nigri
Stefania Ferraro
Ludovico Minati
Davide Rossi
Dunja Duran
Eugenio Parati
Matilde Leonardi
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differential diagnosis between Vegetative State and Minimally Conscious State is a challenging task that requires specific assessment scales, involvement of expert neuropsychologists or physicians and use of tailored stimuli for eliciting behavioural responses. Although misdiagnosis rate as high as 40% has been reported, no clear guidelines are available in literature on the optimal setting for assessment. The present study aims to analyse score differences in behavioural assessments of persons with disorders of consciousness (DOC) with or without family members and to determine whether the presence of caregivers could improve clinical accuracy in diagnostic evaluation. The research was conducted on 92 adults with DOC among 153 consecutive patients enrolled in the Coma Research Centre of the Neurological Institute C. Besta of Milan between January 2011 and May 2013. The results indicate that in almost half of the sample the scoring, thus the performance, observed with caregivers was better than without them. Furthermore, in 16% of the sample, when assessment was performed with caregivers there was a change in diagnosis, from Vegetative to Minimally Conscious State or from that to Severe Disability. Finally, statistical differences were found in relation to diagnosis between mean scores in the "visual function" Coma Recovery Scale revised's subscale obtained by raters plus caregiver and rates only assessment. This study demonstrates how the presence of caregivers can positively affect behavioural assessments of persons with DOC, thus contributing to the definition of the optimal setting for behavioural evaluation of patients, to decrease misdiagnosis rates.

Indexed as

CaregiversDisability EvaluationFamilyAdultConsciousnessConsciousness DisordersDiagnosis, DifferentialFemaleHumansMaleMiddle AgedPersistent Vegetative StatePrognosisProspective StudiesRecovery of FunctionReproducibility of Results

Identifiers

PMID25239389
OpenAlexW2043397355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.