Evidence map›Paper›PMID 25239323›Full record

Trial reportSurgery2014

Thermogenic changes after gastric bypass, adjustable gastric banding or diet alone.

Charlotte Rabl, Madhu N Rao, Jean-Marc Schwarz, Kathleen Mulligan, Guilherme M Campos

Open access · greenAbstract readClinical TrialComparative Study
In one paragraph

Trial report in Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Bile acids and metabolic surgery.Liver research (Beijing, China) · 2021
    Review
  12. Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2020
    Observational
  13. Article
  14. Article
  15. Remission of Type 2 Diabetes Mellitus after Bariatric Surgery: Fact or Fiction?International journal of environmental research and public health · 2019
    Review
  16. Article
  17. Role of Bile Acids in Bariatric Surgery.Frontiers in physiology · 2019
    Review
  18. Article
  19. Article
  20. Blunting of adaptive thermogenesis as a potential additional mechanism to promote weight loss after gastric bypass.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Charlotte RablDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI; Department of Surgery, University of California San Francisco, San Francisco, CA; Department of Surgery, Paracelsus Medical University, Salzburg, Austria.
Madhu N RaoDepartment of Medicine, University of California San Francisco, San Francisco, CA.
Jean-Marc SchwarzDepartment of Medicine, University of California San Francisco, San Francisco, CA; Touro University-California, Vallejo, CA.
Kathleen MulliganDepartment of Medicine, University of California San Francisco, San Francisco, CA.
Guilherme M CamposDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI; Department of Surgery, University of California San Francisco, San Francisco, CA. Electronic address: campos@surgery.wisc.edu.
University of California, San Francisco · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
CTSA: K12 COMPONENTKL2RR024130 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$19.3M
NCATS NIH HHS UL1 TR000004NCRR NIH HHS KL2 RR024130NCRR NIH HHS UL1 RR024131
6 · The paper itself

Abstract

backgroundThe mechanisms by which bariatric surgery achieves weight loss (WL) are under scrutiny. We assessed changes in resting energy expenditure (REE) after gastric bypass (RYGB) and gastric banding (AGB) to determine if changes in REE are associated with WL and type of surgery.

methodsThree groups of morbidly obese patients were studied: RYGB (n = 12), AGB (n = 8), and a control group that underwent caloric restriction alone (Diet, n = 10). Studies were performed at baseline and after 14 days in all groups and 6 months after RYGB and AGB. REE (kcal/day) was measured by indirect calorimetry and adjusted for body weight (Wt-REE), and lean body mass by dual-energy X-ray absorptiometry (LBM-REE).

resultsAt baseline, REE did not differ significantly among groups (RYGB = 2,114 ± 337, AGB = 1,837 ± 154, Diet = 2,091 ± 363 kcal/day, P = .13). After 14 days, the groups had similar percent excess WL (%EWL). Neither Wt-REE nor LBM-REE changed significantly in any group. After 6 months %EWL was 49 ± 10% after RYGB and 21 ± 11% after AGB (P < .01); RYGB patients had greater increase in the percent of weight that was LBM (RYGB = 7.9 ± 3.0 vs. AGB = 1.6 ± 1.5%, P < .01). Wt-REE increased significantly only after RYGB (+2.58 ± 1.51 kcal/kg/day, P < .01). There was a significant correlation between changes in Wt-REE and %EWL (r = 0.670, P = .003).

conclusionThe increase in Wt-REE may be a factor supporting WL after RYGB.

Indexed as

Basal MetabolismGastric BypassGastroplastyAdultCalorimetry, IndirectDiet, ReducingFemaleFollow-Up StudiesHumansMaleMiddle AgedObesity, MorbidTreatment OutcomeWeight Loss

Identifiers

PMID25239323
PMCPMC4171693
OpenAlexW2152895024

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.