Evidence map›Paper›PMID 25239288›Full record

ArticleCerebellum (London, England)2014

Dissecting the links between cerebellum and dystonia.

Ailish Malone, Mario Manto, Chris Hass

Open access · bronzeAbstract readEditorial
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Movement Disorders in Genetic Pediatric Ataxias.Movement disorders clinical practice · 2020
    Review
  4. Review
  5. Observational
  6. Dystonia and ataxia progression in spinocerebellar ataxias.Parkinsonism & related disorders · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Cerebellum: An explanation for dystonia?Cerebellum & ataxias · 2017
    Review
  11. Article
  12. Effects of cerebellar theta-burst stimulation on arm and neck movement kinematics in patients with focal dystonia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016
    Article
  13. Article
  14. Dystonia: Five new things.Neurology. Clinical practice · 2015
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Ailish MaloneGait Laboratory, Central Remedial Clinic, Clontarf, Dublin 3, Ireland.
Mario Manto
Chris Hass
Central Remedial Clinic · IEErasmus Hospital · BEUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dystonia is a common movement disorder characterized by sustained muscle contractions. These contractions generate twisting and repetitive movements or typical abnormal postures, often exacerbated by voluntary movement. Dystonia can affect almost all the voluntary muscles. For several decades, the discussion on the pathogenesis has been focused on basal ganglia circuits, especially striatal networks. So far, although dystonia has been observed in some forms of ataxia such as dominant ataxias, the link between the cerebellum and dystonia has remained unclear. Recent human studies and experimental data mainly in rodents show that the cerebellum circuitry could also be a key player in the pathogenesis of some forms of dystonia. In particular, studies based on behavioral adaptation paradigm shed light on the links between dystonia and cerebellum. The spectrum of movement disorders in which the cerebellum is implicated is continuously expanding, and manipulation of cerebellar circuits might even emerge as a candidate therapy in the coming years.

Indexed as

AnimalsCerebellumDisease Models, AnimalDystonic DisordersHumansLearningMotor Activity

Identifiers

PMID25239288
OpenAlexW2091250955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.