ReviewBehaviour research and therapy2014
The neuroscience of depression: implications for assessment and intervention.
Review in Behaviour research and therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of vortioxetine on the physical symptoms of major depressive disorder.Journal of psychopharmacology (Oxford, England) · 2018Pooled it
- Exercise effects on depression: Possible neural mechanisms.General hospital psychiatry · 2017Pooled it
- Trial
- The impact of sleep and psychiatric symptoms on alcohol consequences among young adults.Addictive behaviors · 2017Trial
- Investigating functional connectivity differences during food vs. monetary reward processing across appetitive phenotypes of major depressive disorder.Journal of affective disorders · 2026Article
- Research Trends and Progress in Exercise Interventions for Depression: A Bibliometric Visualization Analysis.Journal of multidisciplinary healthcare · 2025Review
- Functional connectivity of the pediatric brain.Neuroradiology · 2024Review
- Continuous remote monitoring of neurophysiologic Immersion accurately predicts mood.Frontiers in digital health · 2024Article
- Understanding the benefits of extrinsic emotion regulation in depression.Frontiers in psychology · 2023Review
- Glutamatergic System in Depression and Its Role in Neuromodulatory Techniques Optimization.Frontiers in psychiatry · 2022Review
- Article
- Is NRXN1 Gene Expression an Important Marker of Treatment of Depressive Disorders? A Pilot Study.Journal of personalized medicine · 2021Article
- Virtual Reality Therapy for Depression and Mood in Long-Term Care Facilities.Geriatrics (Basel, Switzerland) · 2021Review
- Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants.Scientific reports · 2020Article
- Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
- Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of Saikosaponin A.Journal of cellular and molecular medicine · 2020Article
- Insula thickness asymmetry relates to risk of major depressive disorder in middle-aged to older adults.Psychiatry research. Neuroimaging · 2019Article
- Increases in orbitofrontal cortex thickness following antidepressant treatment are associated with changes in resting state autonomic function in adolescents with major depression - Preliminary findings from a pilot study.Psychiatry research. Neuroimaging · 2018Article
- Cortico-amygdalar maturational coupling is associated with depressive symptom trajectories during adolescence.NeuroImage · 2017Article
- Functional Circuitry Effect of Ventral Tegmental Area Deep Brain Stimulation: Imaging and Neurochemical Evidence of Mesocortical and Mesolimbic Pathway Modulation.Frontiers in neuroscience · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
Major Depressive Disorder (MDD) is among the most prevalent of all psychiatric disorders and is the single most burdensome disease worldwide. In attempting to understand the profound deficits that characterize MDD across multiple domains of functioning, researchers have identified aberrations in brain structure and function in individuals diagnosed with this disorder. In this review we synthesize recent data from human neuroimaging studies in presenting an integrated neural network framework for understanding the impairments experienced by individuals with MDD. We discuss the implications of these findings for assessment of and intervention for MDD. We conclude by offering directions for future research that we believe will advance our understanding of neural factors that contribute to the etiology and course of depression, and to recovery from this debilitating disorder.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.