Evidence map›Paper›PMID 25239147›Full record

ArticleMolecular and cellular biochemistry2014

Endothelial progenitor cells as a possible component of stem cell niche to promote self-renewal of mesenchymal stem cells.

Hongwei Zhang, Lingling Xian, Zhiyi Lin, Chaozhe Yang, Meng Zhang, Wenlei Feng, Xinyu Peng, Xueling Chen, Xiangwei Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Endogenous Stem Cells in Homeostasis and Aging.Tissue engineering and regenerative medicine · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongwei ZhangTongji Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Lingling Xian
Zhiyi Lin
Chaozhe Yang
Meng Zhang
Wenlei Feng
Xinyu Peng
Xueling Chen
Xiangwei Wu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells dwell at the "stem cell niche" to accomplish a series of biological processes. The composition of the niche should be determined because the insufficient understanding of this feature limits the development in the study of stem cells. We showed in our study on mesenchymal stem cells (MSCs) that the MSCs first neighbored to CD31(+) cells, which proved to be endothelial progenitor cells (EPCs), and formed a group of cell colony before they exerted their biological functions. It was further proved that EPCs have close interactions with MSCs and promoted the self-renewal of the MSCs in vitro and in vivo. Together with these achievements, we hypothesized that EPCs may be a possible biological component of the MSC stem cell niche and affect the biological processes of MSCs.

Indexed as

AnimalsEndothelial CellsMesenchymal Stem CellsMiceMice, KnockoutStem Cell Niche

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.