Evidence map›Paper›PMID 25238990›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2015

Effect of dose reduction on image registration and image quality for cone-beam CT in radiotherapy.

B Loutfi-Krauss, J Köhn, N Blümer, K Freundl, T Koch, E Kara, C Scherf, C Rödel, U Ramm, J Licher

Abstract read
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In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Prerequisites for the clinical implementation of a markerless SGRT-only workflow for the treatment of breast cancer patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

B Loutfi-KraussKlinik für Strahlentherapie und Onkologie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
J Köhn
N Blümer
K Freundl
T Koch
E Kara
C Scherf
C Rödel
U Ramm
J Licher
Goethe University Frankfurt · DEUniversity Hospital Frankfurt · DESozialstiftung Bamberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe additional radiation exposure applied to patients undergoing cone-beam computed tomography (CBCT) for image registration in radiation therapy is of great concern. Since a decrease in CBCT dose is linked to a degradation of image quality, the consequences of dose reduction on the registration process have to be investigated. MATERIAL AND

methodsThis paper examines image quality and registration of low-contrast structures on an Elekta XVI for the two treatment areas prostate and chest while gradually decreasing the mAs per frame and the number of projections per CBCT to achieve dose reduction.

resultsIdeal results for image quality were obtained for 1.6 mAs/frame and 377 projections in prostate scans and 0.63 mAs/frame and 440 projections in chest images. Lower as well as higher total mAs lead to a decrease in image quality. In spite of poor image quality, registration can be successfully performed even for lowest possible settings.

conclusionThe results for registration allow an extensive dose reduction in both treatment areas. Very low mAs, however, do not qualify for clinical use because subjective judgment of the registration process is impossible. Compared to default presets the use of settings for acceptable image quality already permit a decrease in exposure of about 40 % (29.0 to 16.7 mGy) in prostate scans and 60 % (18.3 to 7.7 mGy) in chest scans.

Indexed as

Image EnhancementRadiation DosageAlgorithmsCone-Beam Computed TomographyFeasibility StudiesHumansMalePhantoms, ImagingProstatic NeoplasmsRadiotherapy Planning, Computer-AssistedThoracic Neoplasms

Identifiers

PMID25238990
OpenAlexW138788335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.