SynthesisPloS one2014
Alcohol intake and the risk of age-related cataracts: a meta-analysis of prospective cohort studies.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between obesity and age-related cataract: an updated systematic review and dose-response meta-analysis of prospective cohort studies.Frontiers in nutrition · 2023Pooled it
- Alcohol and Health Outcomes: An Umbrella Review of Meta-Analyses Base on Prospective Cohort Studies.Frontiers in public health · 2022Pooled it
- Association between dietary magnesium intake and risk of cataract surgery: data from NHANES 2003-2008.Eye (London, England) · 2025Article
- Predictors of Cataract Surgery Among US Adults: NHANES 2007-2008.Healthcare (Basel, Switzerland) · 2025Article
- Sex-specific social, lifestyle, and physical health risk factors in cataracts development.Eye (London, England) · 2024Article
- Alcohol use patterns and risk of incident cataract surgery: a large scale case-control study in Japan.Scientific reports · 2022Article
- Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study.Scientific reports · 2022Article
- Alcohol Consumption and Incident Cataract Surgery in Two Large UK Cohorts.Ophthalmology · 2021Observational
- FACTORS ASSOCIATED WITH PREVALENT LENS OPACITIES IN CHINESE AMERICAN ADULTS: THE CHINESE AMERICAN EYE STUDY.Ophthalmic epidemiology · 2021Article
- Intake of Vegetables and Fruits and the Risk of Cataract Incidence in a Japanese Population: The Japan Public Health Center-Based Prospective Study.Journal of epidemiology · 2021Article
- Prevalence of Self-Reported Diagnosed Cataract and Associated Risk Factors among Elderly South Africans.International journal of environmental research and public health · 2017Article
- Risk Factors for Cataracts Treated Surgically in Postmenopausal Women.Ophthalmology · 2016Article
- Alcohol consumption and dry eye syndrome: a Meta-analysis.International journal of ophthalmology · 2016Article
- Causal effect of gastroesophageal reflux disease on cataracts: A mendelian randomization study.Advances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEpidemiologic studies assessing the relationship between alcohol consumption and the risk of age-related cataracts (ARCs) led to inconsistent results. This meta-analysis was performed to fill this gap.
methodsEligible studies were identified via computer searches and reviewing the reference lists of these obtained articles. Pooled estimates of the relative risks (RR) and the corresponding 95% confidence Intervals (CI) were calculated using random effects models.
resultsSeven prospective cohort studies involving a total of 119,706 participants were ultimately included in this meta-analysis. Pooled results showed that there is no substantial overall increased risk of ARC due to heavy alcohol consumption. The estimated RRs comparing heavy drinkers versus non-drinkers were 1.25 (95% CI: 1.00, 1.56) for cataract sugery, 1.06 (95% CI: 0.63, 1.81) for cortical cataracts, 1.26 (95% CI: 0.93, 1.73) for nuclear cataracts, and 0.91 (95% CI: 0.32, 2.61) for posterior subcapsular cataracts (PSCs), respectively. No significant associations between moderate alcohol consumption and cataracts were observed. The pooled RRs comparing moderate drinkers versus non-drinkers were 0.90 (95% CI: 0.64, 1.26) for cataract surgery, 0.97 (95% CI: 0.75, 1.25) for cortical cataracts, 0.91 (95% CI: 0.76, 1.08) for nuclear cataracts, and 0.97 (95% CI: 0.49, 1.91) for PSCs, respectively.
conclusionsThis meta-analysis suggests that there is no substantial overall increased risk of ARC due to alcohol intake. Because of the limited number of studies, the findings from our study must be confirmed in future research via well-designed cohort or intervention studies.
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