SynthesisPloS one2014
Effect of black tea consumption on blood cholesterol: a meta-analysis of 15 randomized controlled trials.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Pooled it
- Polyphenol Consumption and Its Association with Physical and Mental Health in Adults with Major Depressive Disorder.Nutrients · 2025Article
- The role of tea in managing cardiovascular risk factors: potential benefits, mechanisms, and interventional strategies.Frontiers in nutrition · 2025Review
- Cholesterol Absorption Inhibition by Some Nutraceuticals.Recent advances in food, nutrition & agriculture · 2025Review
- Investigating the relationship between liver health status with coffee and tea consumption in participants referred to the Rafsanjan Cohort study in Iran.Scientific reports · 2024Article
- Tea consumption and the risk of abdominal aortic aneurysm.The British journal of surgery · 2022Article
- The effect of Cistus incanus herbal tea supplementation on oxidative stress markers and lipid profile in healthy adults.Cardiology journal · 2021Article
- The Association between Green and Black Tea Consumption on Successful Aging: A Combined Analysis of the ATTICA and MEDiterranean ISlands (MEDIS) Epidemiological Studies.Molecules (Basel, Switzerland) · 2019Article
- The Possible Role of Nutraceuticals in the Prevention of Cardiovascular Disease.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019Review
- Dietary Polyphenols in the Prevention of Stroke.Oxidative medicine and cellular longevity · 2017Review
- Effects of Polyphenol Intake on Metabolic Syndrome: Current Evidences from Human Trials.Oxidative medicine and cellular longevity · 2017Review
- Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review.Circulation · 2016Review
- Endothelin-A receptor antagonists in prostate cancer treatment-a meta-analysis.International journal of clinical and experimental medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe results of the studies that have investigated the effects of black tea on blood cholesterol are inconsistent. The aim of this study is to quantitatively assess the effects of black tea on cholesterol concentrations.
methodsPubMed, Embase, MEDLINE, and Cochrane Library (through to July 2014) were searched for randomized controlled trials (RCTs) designed to investigate the effect of black tea on blood cholesterol concentrations. The study quality was assessed by the Jadad scoring criteria. Pooled effect of black tea consumption on blood cholesterol concentrations was evaluated by fixed-effects or random-effects model. Meta-regression analyses were conducted to estimate dose effects of black tea polyphenols on concentrations of blood cholesterol. Subgroup and sensitivity analyses were performed to assess the potential source of heterogeneity.
resultsThe consumption of black tea did not significantly lower TC concentrations either in healthy subjects or patients with coronary artery diseases based on both fixed-effects and random-effects analysis. No significant change was observed in HDL-C concentrations in healthy participants or in subjects with coronary artery disease supplemented with black tea when compared with control participants. The pooled net change of LDL-C in healthy participants was -5.57 mg/dL (95% CI, -9.49 to -1.66 mg/dL; P = 0.005) in fixed-effects analysis and -4.56 (95% CI, -10.30 to 1.17 mg/dL; P = 0.12) in random-effects analysis. No significant net change was observed in LDL-C concentrations in patients with coronary artery disease. Subgroup and sensitivity did not significantly influence the overall outcomes of this meta-analysis. No significant dose effects of black tea polyphenols on blood cholesterol concentrations were detected in meta-regression analyses.
conclusionThe meta-analysis suggests that the consumption of black tea might not have beneficial effects on concentrations of TC, HDL-C, and LDL-C. Further high quality RCTs are needed to definitively draw a causal interpretation of the findings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.