ArticleCognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology2014
Feelings without memory in Alzheimer disease.
Article in Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03643003 (Music Therapy for Persons With Dementia), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Music Therapy for Persons With Dementia: A Randomized Clinical Crossover Trial
Who cites it
20 citing papers in PubMed, 89 citations in OpenAlex.
- Emotional enhancement of memory in Alzheimer's disease dementia: a systematic review.Nature. Mental health · 2025Article
- Co-creating Humanistic AI AgeTech to Support Dynamic Care Ecosystems: A Preliminary Guiding Model.The Gerontologist · 2024Article
- Establishing the Foundations of Emotional Intelligence in Care Companion Robots to Mitigate Agitation Among High-Risk Patients With Dementia: Protocol for an Empathetic Patient-Robot Interaction Study.JMIR research protocols · 2024Article
- Exploring medical students' perceptions of empathy after cinemeducation based on Vygotsky's theory.BMC medical education · 2024Article
- Study on Associating Emotions in Verbal Reactions to Facial Expressions in Dementia.Healthcare (Basel, Switzerland) · 2022Article
- Methods and approaches for enhancing communication with people with moderate-to-severe dementia that can facilitate their inclusion in research and service evaluation: Findings from the IDEAL programme.Dementia (London, England) · 2022Article
- Aesthetic Preference for Negatively-Valenced Artworks Remains Stable in Pathological Aging: A Comparison Between Cognitively Impaired Patients With Alzheimer's Disease and Healthy Controls.Frontiers in psychology · 2022Article
- Emotional Valence Affects Word Retrieval During Verb Fluency Tasks in Alzheimer's Dementia.Frontiers in psychology · 2021Article
- The Seven Selves of Dementia.Frontiers in psychiatry · 2021Review
- 'I am your son, mother': severe dementia and duties to visit parents who can't recognise you.Medicine, health care, and philosophy · 2020Article
- Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2018Article
- Early affective changes and increased connectivity in preclinical Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2018Article
- A novel two-day intervention reduces stress in caregivers of persons with dementia.Alzheimer's & dementia (New York, N. Y.) · 2018Article
- Intergenerational Programs May Be Especially Engaging for Aged Care Residents With Cognitive Impairment: Findings From the Avondale Intergenerational Design Challenge.American journal of Alzheimer's disease and other dementias · 2017Article
- Couples' Social Careers in Assisted Living: Reconciling Individual and Shared Situations.The Gerontologist · 2016Article
- Reach the Person behind the Dementia - Physical Therapists' Reflections and Strategies when Composing Physical Training.PloS one · 2016Article
- Decreased expression of the APOA1-APOC3-APOA4 gene cluster is associated with risk of Alzheimer's disease.Drug design, development and therapy · 2015Article
- Serum calreticulin is a negative biomarker in patients with Alzheimer's disease.International journal of molecular sciences · 2014Article
- Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology.American journal of Alzheimer's disease and other dementiasReview
- Music-Evoked Autobiographical Memories are Associated with Negative Affect in Younger and Older Adults.Experimental aging researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatients with Alzheimer disease (AD) typically have impaired declarative memory as a result of hippocampal damage early in the disease. Far less is understood about AD's effect on emotion.
objectiveWe investigated whether feelings of emotion can persist in patients with AD, even after their declarative memory for what caused the feelings has faded.
methodsA sample of 17 patients with probable AD and 17 healthy comparison participants (case-matched for age, sex, and education) underwent 2 separate emotion induction procedures in which they watched film clips intended to induce feelings of sadness or happiness. We collected real-time emotion ratings at baseline and at 3 post-induction time points, and we administered a test of declarative memory shortly after each induction.
resultsAs expected, the patients with AD had severely impaired declarative memory for both the sad and happy films. Despite their memory impairment, the patients continued to report elevated levels of sadness and happiness that persisted well beyond their memory for the films. This outcome was especially prominent after the sadness induction, with sustained elevations in sadness lasting for more than 30 minutes, even in patients with no conscious recollection for the films.
conclusionsThese findings indicate that patients with AD can experience prolonged states of emotion that persist well beyond the patients' memory for the events that originally caused the emotion. The preserved emotional life evident in patients with AD has important implications for their management and care, and highlights the need for caretakers to foster positive emotional experiences.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.