ArticleThe world journal of men's health2014
Effects of tamsulosin on premature ejaculation in men with benign prostatic hyperplasia.
Article in The world journal of men's health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Seminal vesicles - an overlooked pair of accessory glands in male sexual dysfunction: a narrative review.International journal of impotence research · 2025Review
- Drug-Induced Sexual Dysfunction: An Analysis of Reports to a National Pharmacovigilance Database.Drug safety · 2022Article
- Oxytocin receptor antagonists as a novel pharmacological agent for reducing smooth muscle tone in the human prostate.Scientific reports · 2021Article
- Emerging and investigational drugs for premature ejaculation.Translational andrology and urology · 2016Review
- The drug treatment of premature ejaculation.Translational andrology and urology · 2016Review
- Prevalence and factor association of premature ejaculation among adult Asian males with lower urinary tract symptoms.Prostate international · 2015Article
- Effect of tadalafil 5mg daily treatment on the ejaculatory times, lower urinary tract symptoms and erectile function in patients with erectile dysfunction.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious studies have revealed that tamsulosin is effective in improving lower urinary tract symptoms (LUTS) and erectile functioning but has some inhibitory effects on ejaculation, including decreased ejaculatory volume. However, these inhibitory effects on ejaculation can be beneficial to patients with premature ejaculation (PE). Therefore, this study was conducted to understand the effect of tamsulosin on PE in men with benign prostatic hyperplasia. MATERIALS AND
methodsTwenty-nine patients who visited with LUTS were categorized into 2 groups of LUTS-only patients (n=12) and LUTS combined with PE (LUTS+PE) patients (n=17), and 0.4 mg of tamsulosin was administered to the patients of both groups for 12 weeks. Comparative analyses of before and after the treatment were conducted for calculating the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), intravaginal ejaculatory latency time (IELT), premature ejaculation diagnostic tool (PEDT), and premature ejaculation profile (PEP). The patients with an IPSS score of 8 or higher were determined as LUTS patients, and the patients with IELT of less than 2 minutess and a PEDT score of 9 or higher were determined as PE patients.
resultsAfter treatment, the IPSS score significantly decreased in both groups. There was no statistically significant change in the PEDT for the LUTS group, but there was a significant decrease in PEDT (p=0.012; from 12.1±3.31 to 8.4±4.49) in the LUTS+PE group.
conclusionsTamsulosin not only has a treatment effect for LUTS but also improves the PE of LUTS+PE patients. Therefore, further studies are needed to confirm the effects of tamsulosin on PE.
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