ArticleAnesthesiology and pain medicine2014
The effect of single-dose administration of dexamethasone on postoperative pain in patients undergoing laparoscopic cholecystectomy.
Article in Anesthesiology and pain medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07257406 (The Use of Intravenous Dexamethasone for Post-operative Pain After Cesarean Delivery Under Neuraxial Anesthesia.), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Use of Intravenous Dexamethasone for Post-operative Pain After Cesarean Delivery Under Neuraxial Anesthesia.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of preoperative ketamine gargle to reduce postoperative sore throat in adult patients undergoing surgery with endotracheal tube; systematic review and meta-analysis of randomized control trials.BMC anesthesiology · 2024Pooled it
- Evidence Map of Pharmacologic and Non-Pharmacologic Perioperative Strategies for Managing Acute Postoperative Pain After Laparoscopic Surgery, 2012-2025: The M-PALS Collaborative.Journal of clinical medicine · 2026Review
- Clarifying the postsurgical persistent pain after laparoscopic cholecystectomy and the role of intravenous lidocaine.Pain reports · 2025Article
- The Effect of Dexamethasone Administration on Postoperative Pain Following Laparoscopic Cholecystectomy: A Double-Blind Randomized Clinical Trial.Advanced biomedical research · 2025Article
- The effect of dexamethasone and bupivacaine on postoperative pain and nausea and vomiting by preperitoneal nerve blocking in laparoscopic cholecystectomy: a randomized clinical trial.Annals of medicine and surgery (2012) · 2024Article
- Effectiveness of perineural administration of dexamethasone with lidocaine on onset time of sensory block and early postoperative analgesia in axillary brachial plexus block: a prospective cohort study, Ethiopia.Annals of medicine and surgery (2012) · 2024Article
- The Effect of Dexamethasone on Postoperative Pain in Patients After Laparoscopic Cholecystectomy.Cureus · 2022Article
- Comparison of Intraperitoneal Versus Intravenous Dexamethasone on Postoperative Pain, Nausea, and Vomiting After Laparoscopic Cholecystectomy.Anesthesiology and pain medicine · 2022Article
- Parecoxib Shortens the Duration of Acute Postoperative Pain After Laparoscopic-Assisted Vaginal Hysterectomy.Frontiers in pharmacology · 2019Article
- The effects of a combination of intravenous dexamethasone and ketamine on postoperative mood in patients undergoing laparoscopically assisted-gynecologic surgery.Psychopharmacology · 2018Article
- Article
- The efficacy of dexamethasone injection on postoperative pain in lower third molar surgery.Journal of dental anesthesia and pain medicine · 2016Article
- Effect of Hydroalcoholic Leaves Extract of Rhus Coriaria on Pain in Male Rats.Anesthesiology and pain medicine · 2016Article
- Impact of duloxetine and dexamethasone for improving postoperative pain after laparoscopic gynecological surgeries: A randomized clinical trial.Saudi journal of anaesthesiaArticle
- Dexamethasone in anesthesia practice: A narrative review.Journal of anaesthesiology, clinical pharmacologyReview
- The Effect of Single-dose Intravenous Dexamethasone on Postoperative Pain and Postoperative Nausea and Vomiting in Patients Undergoing Surgery under Spinal Anesthesia: A Double-blind Randomized Clinical Study.Anesthesia, essays and researchesArticle
- Effect of preemptive analgesia with intravenous oxycodone in the patients undergoing laparoscopic resection of ovarian tumor.Pakistan journal of medical sciencesArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative pain is considered as a reason of patient's delay in discharge and disability aggravation. Therefore, multimodal approaches have been suggested in order to mitigate pain and decrease postoperative side effects.
objectivesThe aim of this study was to evaluate analgesic effect of a single dose injection of dexamethasone on reducing postoperative pain in laparoscopic cholecystectomy. PATIENTS AND
methodsIn this double-blind, prospective study, 122 patients aged 18-60 years old, whom were selected for laparoscopic cholecystectomy, were classified into two case and control groups, and 61 patients were included in each group. The case (D) group underwent general anesthesia and a single- dose intravenous injection of dexamethasone. The Control (C) group received general anesthesia and intravenous injection of normal saline. Total dose of consumed meperidine and pain intensity during first 24 hours were evaluated in both groups.
resultsNo significant difference existed between two groups regarding age, sex, weight and operation time. Pain intensity in group D was significantly less than group C (P < 0.01) after two, six and 12 hoursof surgery. No significant difference existed in pain intensity between two groups at the beginning of and 24 hours after the surgery (P > 0.05). Meperidine consumption in group D was significantly less than group C (P < 0.05).
conclusionsFindings of present study showed that single dose of intravenous dexamethasone, led to less pain intensity and amounts of meperidine consumption, in comparison with placebo.
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