Evidence map›Paper›PMID 25237502›Full record

ArticlePsychiatric bulletin (2014)2014

Unheard voices: outcomes of tertiary care for treatment-refractory psychosis.

S Neil Sarkar, Derek K Tracy, Maria-Jesus Mateos Fernandez, Natasza Nalesnik, Gurbinder Dhillon, Juliana Onwumere, Anne-Marye Prins, Karen Schepman, Tracy Collier, Thomas P White and 3 more

Abstract read
In one paragraph

Article in Psychiatric bulletin (2014), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

S Neil SarkarCentral and North West London NHS Foundation Trust ; Cognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Derek K TracyCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London ; Oxleas NHS Foundation Trust, London.
Maria-Jesus Mateos FernandezCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Natasza NalesnikCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Gurbinder DhillonOxleas NHS Foundation Trust, London.
Juliana OnwumereSouth London and Maudsley NHS Foundation Trust.
Anne-Marye PrinsSouth London and Maudsley NHS Foundation Trust.
Karen SchepmanCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Tracy CollierCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Thomas P WhiteCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London.
Anita PatelHealth Service and Population Research Department, Institute of Psychiatry, King's College London.
Fiona GaughranSouth London and Maudsley NHS Foundation Trust.
Sukhwinder S ShergillCognition, Schizophrenia and Imaging Laboratory, Department of Psychosis Studies, Institute of Psychiatry, King's College London ; South London and Maudsley NHS Foundation Trust.

Funding

Medical Research Council G0901868
6 · The paper itself

Abstract

Aims and method In up to a quarter of patients, schizophrenia is resistant to standard treatments. We undertook a naturalistic study of 153 patients treated in the tertiary referral in-patient unit of the National Psychosis Service based at the Maudsley Hospital in London. A retrospective analysis of symptoms on admission and discharge was undertaken using the OPCRIT tool, along with preliminary economic modelling of potential costs related to changes in accommodation. Results In-patient treatment demonstrated statistically significant improvements in all symptom categories in patients already identified as having schizophrenia refractory to standard secondary care. The preliminary cost analysis showed net savings to referring authorities due to changes from pre- to post-discharge accommodation. Clinical implications Despite the enormous clinical, personal and societal burden of refractory psychotic illnesses, there is insufficient information on the outcomes of specialised tertiary-level care. Our pilot data support its utility in all domains measured.

Identifiers

PMID25237502
PMCPMC4115394

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.