ArticleMediterranean journal of hematology and infectious diseases2014
Predictors of Mortality in Mechanically Ventilated Critical Pertussis in a low Income Country.
Article in Mediterranean journal of hematology and infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Variability in the Diagnostic Criteria for Severe Pertussis: A Systematic Review.JAMA network open · 2026Pooled it
- Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score.Critical care (London, England) · 2025Pooled it
- Burden of pertussis in infants in the Eastern Mediterranean Region and the impact of maternal vaccination: a systematic review.BMC public health · 2025Pooled it
- Cerebral venous thrombosis in infant with pertussis: A rare complication in a hyperleukocytosis and thrombocytosis Storm, A threshold worth defining.Hematology, transfusion and cell therapy · 2026Article
- Clinical Profile, Outcome and Risk Factors for Mortality Among Children Admitted with Critical Pertussis: An Ambispective Study.Indian pediatrics · 2026Article
- Clinical features, disease severity, and outcomes of pertussis in hospitalized children: A retrospective study from Serbia.PloS one · 2026Article
- Critical pertussis infection in the paediatric intensive care unit: A case series in an outbreak.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025Article
- Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India.Indian pediatrics · 2020Article
- Leukemoid Reaction in Infant Pertussis: Is There a Place for Hydroxyurea? A Case Report.Frontiers in pediatrics · 2018Article
- Pertussis leukocytosis: mechanisms, clinical relevance and treatment.Pathogens and disease · 2016Review
- Bordetella pertussis: new concepts in pathogenesis and treatment.Current opinion in infectious diseases · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCritical pertussis is characterized by severe respiratory failure, important leukocytosis, pulmonary hypertension, septic shock and encephalopathy.
aimTo describe the clinical course of critical pertussis, and identify predictors of death at the time of presentation for medical care. METHODOLOGY: Retrospective study conducted in children's hospital Tunisian PICU between 01 January and 31 October 2013. Patients with critical pertussis confirmed by RT-PCR and requiring mechanical ventilation were included. Predictors of death were studied.
resultsA total of 17 patients was studied. Median age was 50 days. Mortality was 23%. Predictors risk of mortality were : high PRISM score (Pediatric Risk of Mortality Score) (p=0,007), shock (p=0,002), tachycardia (p=0,005), seizures (p=0,006), altered mental status (p=0,006), elevated WBC count (p=0,003) and hemodynamic support (p=0022). However, the difference did not reach statistical significance in comorbidity, pneumoniae, high pulmonary hypertension or exchange transfusion. Concomitant viral or bacterial co-infection was not related to poor outcome.
conclusionYoung infants are at high risk to have critical pertussis. Despite advances in life support and the treatment of organ failure in childhood critical illness, critical pertussis remains difficult to treat.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.