Evidence map›Paper›PMID 25237406›Full record

ArticleOpen medicine : a peer-reviewed, independent, open-access journal2013

Trends in HIV prevalence, new HIV diagnoses, and mortality among adults with HIV who entered care in Ontario, 1996/1997 to 2009/2010: a population-based study.

Tony Antoniou, Brandon Zagorski, Ahmed M Bayoumi, Mona R Loutfy, Carol Strike, Janet Raboud, Richard H Glazier

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Open medicine : a peer-reviewed, independent, open-access journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Variability in Human Immunodeficiency Virus infection screening: impact of the COVID-19 pandemic.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tony AntoniouTony Antoniou, PhD, is a Research Scholar in the Department of Family and Community Medicine and a Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, and an Assistant Professor in the Department of Family and Community Medicine and the Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.
Brandon ZagorskiBrandon Zagorski, MSc, is an Adjunct Professor in the Faculty of Medicine, University of Toronto, Toronto, Ontario. At the time of this study, he was also an Analyst with the Institute for Clinical Evaluative Sciences, Toronto, Ontario.
Ahmed M BayoumiAhmed M. Bayoumi is a Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute and Centre for Research on Inner City Health, St. Michael's Hospital, and an Associate Professor in the Department of Medicine and the Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario.
Mona R LoutfyMona R. Loutfy, MD, MPH, is an Associate Professor in the Department of Medicine, University of Toronto, and a Scientist at the Women's College Hospital Research Institute, Toronto, Ontario.
Carol StrikeCarol Strike, PhD, is an Associate Professor in the Dalla Lana School of Public Health, University of Toronto, and an Affiliate Scientist in the Health Systems and Health Equity Research Group, Centre for Addiction and Mental Health, Toronto, Ontario.
Janet RaboudJanet Raboud, PhD, is an Affiliate Scientist at the Toronto General Research Institute and an Associate Professor in the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario.
Richard H GlazierRichard H. Glazier, MD, MPH, is a Professor and Clinician Scientist in the Department of Family and Community Medicine, University of Toronto and St. Michael's Hospital, a Senior Scientist at the Institute for Clinical Evaluative Sciences, and a Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute and Centre for Research on Inner City Health, St. Michael's Hospital, Toronto, Ontario.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPopulation-based estimates of HIV prevalence, rates of new HIV diagnoses, and mortality rates among persons with HIV who have entered care are needed to optimize health service delivery and to improve the health outcomes of these individuals. However, these data have been lacking for Ontario.

methodsUsing a validated case-finding algorithm and linked administrative health care databases, we conducted a population-based study to determine the prevalence of HIV and rates of new HIV diagnoses among adults aged 18 years or older in Ontario between fiscal year 1996/1997 and fiscal year 2009/2010, as well as all-cause mortality rates among persons with HIV over the same period.

resultsBetween 1996/1997 and 2009/2010, the number of adults living with HIV increased by 98.6% (from 7608 to 15,107), and the age- and sex-standardized prevalence of HIV increased by 52.8% (from 92.8 to 141.8 per 100,000 population; p < 0.001). Women and individuals 50 years of age or older accounted for increasing proportions of persons with HIV, rising from 12.8% to 19.7% (p < 0.001) and from 10.4% to 29.9% (p < 0.001), respectively, over the study period. During the study period, age- and sex-standardized rates of new HIV diagnoses decreased by 32.5% (from 12.3 to 8.3 per 100,000 population; p < 0.001) and mortality rates among adults with HIV decreased by 71.9% (from 5.7 to 1.6 per 100 adults with HIV; p < 0.001).

interpretationThe prevalence of HIV infection in Ontario increased considerably between 1996/1997 and 2009/2010, with a greater relative burden falling on women and individuals aged 50 years of age or older. These trends may be due to the decreased rate of new diagnoses among younger men. All-cause mortality rates declined among persons with HIV who entered care.

Indexed as

AdolescentAdultCohort StudiesFemaleHIV InfectionsHumansIncidenceMaleMiddle AgedOntarioPrevalenceYoung Adult

Identifiers

PMID25237406
PMCPMC4161501

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.