ArticleInternational journal of endocrinology and metabolism2014
Predictors of acute kidney injury in geriatric patients undergoing total knee replacement surgery.
Article in International journal of endocrinology and metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 25 citations in OpenAlex.
- Acute Kidney Injury After Total Hip and Knee Arthroplasty. What Is the Culprit?Arthroplasty today · 2024Article
- Is there an optimal age for total knee arthroplasty?: A systematic review.Knee surgery & related research · 2020Article
- Acute Deterioration of Kidney Function after Total Hip Arthroplasty.Malaysian orthopaedic journal · 2020Article
- Clinical Conundrums in the Management of Diabetic Ketoacidosis in the Elderly.Journal of translational internal medicine · 2019Article
- Acute Kidney Injury in Patients Undergoing Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2019Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have focused on patients' characteristics that affects acute kidney injury (AKI) after total knee replacement surgery (TKR).
objectivesThe primary objective of this retrospective study was to identify patients' characteristics associated with AKI after TKR. PATIENTS AND
methodsBetween January 2008 and December 2009, 659 patients with a mean age of 67.1 years (range, 39-99) underwent TKA at Regional Hospital Knee and Hip Institute. Retrospective chart review was done to identify patients' characteristics that were associated with AKI after TKR. Logistic regression was used to evaluate AKI.
resultsAKI occurred in 21.9% of patients. AKI risk decreased between 2008 and 2009 (odds ratio, 0.55; 95% CI, -0.37 to 0.82) but increased with age (P < 0.001), diabetes mellitus (DM), and angiotensin converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) use (OR, -1.6; 95% CI, -1.0 to 2.5; and OR, -1.5, 95% CI, -1.0 to 2.3, respectively). However, the effects of DM and ACEI/ARB use were not independent; when both were included in the regression model, neither was statistically significant, and both ORs were smaller than combined OR.
conclusionsWhen examined separately, both DM and preoperative ACEI/ARB use increased the risk of AKI; however these factors were correlated and were not independent predictors of significantly increased risk. Patients with DM have higher tendency to develop AKI and hence, preoperative renal risk stratification should be done in all patients with DM.
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