ArticleEuropean journal of applied physiology2015
Mouth rinsing with a bitter solution without ingestion does not improve sprint cycling performance.
Article in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Effects of Carbohydrate Mouth Rinse on Human Capacity and Performance-A Systematic Review and Meta-Analysis of 90 Controlled Trials.Nutrients · 2026Pooled it
- Effects of Caffeine Dose and Administration Method on Time-Trial Performance: A Systematic Review and Network Meta-Analysis.Nutrients · 2025Pooled it
- Mouth rinsing and ingesting salty or bitter solutions does not influence corticomotor excitability or neuromuscular function.European journal of applied physiology · 2023Trial
- A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.Journal of the International Society of Sports Nutrition · 2026Review
- Central effects of mouth rinses on endurance and strength performance.European journal of applied physiology · 2024Review
- A Narrative Review of Current Concerns and Future Perspectives of the Carbohydrate Mouth Rinse Effects on Exercise Performance.SAGE open medicine · 2022Review
- Can taste be ergogenic?European journal of nutrition · 2021Review
- Muscle Sentry® has No Effect on Total Work Performed and Estimated MVOInternational journal of exercise science · 2020Article
- New Insights into Enhancing Maximal Exercise Performance Through the Use of a Bitter Tastant.Sports medicine (Auckland, N.Z.) · 2016Review
- Mouth rinsing and ingestion of a bitter-tasting solution increases corticomotor excitability in male competitive cyclists.European journal of applied physiology · 2015Article
- A Pre-Exercise Dose of Muscle SentryInternational journal of exercise scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRecently, we have shown that combining mouth rinsing with the ingestion of a 2 mM quinine solution immediately before a 30-s cycling sprint significantly improves performance. However, the strong bitterness of such a solution produces an unpleasant taste and evokes nausea at higher concentrations. Given the possibility that mouth rinsing with quinine without ingesting it may not produce nausea, a mouth rinse only protocol may be a more practical approach to administer quinine for improving exercise performance. The purpose of the present study was to determine whether mouth rinsing with quinine without ingesting it improves 30-s sprint cycling performance.
methodsTwelve competitive male cyclists performed a 30-s maximal cycling sprint immediately after rinsing their mouth for 10 s with either a 10 mM bitter quinine solution (QUI), plain water (WAT), a 7.1 % w/v sweet glucose solution (GLU), or no solution at all (control; CON). Sprint performance was assessed, and heart rate, ratings of perceived exertion and blood variables were measured pre- and post-exercise.
resultsMean power output during the 30-s sprint (QUI 888 ± 38; CON 873 ± 39; WAT 885 ± 37; GLU 873 ± 42 W; p = 0.431) as well as peak power (QUI 1230 ± 61; CON 1,208 ± 65; WAT 1,220 ± 70; GLU 1,202 ± 59 W; p = 0.690) were similar between the four conditions. There were no significant differences in any other performance measures, heart rate, subjective ratings or blood variables between conditions.
conclusionsMouth rinsing with a bitter tasting quinine solution without ingestion does not improve 30-s sprint cycling performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.