ArticleG3 (Bethesda, Md.)2014
Structures of naturally evolved CUP1 tandem arrays in yeast indicate that these arrays are generated by unequal nonhomologous recombination.
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Multi-omics insights into bacterial and fungal bioremediation of Potentially Toxic Elements (PTEs): a critical overview of their applications.World journal of microbiology & biotechnology · 2026Review
- Parallel gene amplification by Cas9 nickase for generating functionally heterogeneous cell populations.Cell reports methods · 2026Article
- From Oak to Wine: Evolution, Admixture, and Adaptation of California and British Columbia Saccharomyces Cerevisiae Wine Strains.Genome biology and evolution · 2026Article
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- Harnessing the Enzymatic Potential of Indigenous Yeast Strains: Screening and Evaluation for Biocontrol and Oenological Advancements.Microorganisms · 2026Article
- Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats.FEMS yeast research · 2026Article
- Transcriptional capacity limits copper resistance in yeast harboring highly expandedmicroPublication biology · 2026Article
- The effect of spontaneous mutations onbioRxiv : the preprint server for biology · 2025Article
- Colonization of vineyards by non-bioRxiv : the preprint server for biology · 2025Article
- Core gene set of the speciesbioRxiv : the preprint server for biology · 2025Article
- Strategic targeting of Cas9 nickase expands tandem gene arrays.Cell genomics · 2025Article
- Article
- The distribution of beneficial mutational effects between two sister yeast species poorly explains natural outcomes of vineyard adaptation.bioRxiv : the preprint server for biology · 2024Article
- Nonlethal Furfural Exposure Causes Genomic Alterations and Adaptability Evolution in Saccharomyces cerevisiae.Microbiology spectrum · 2023Article
- Whole genome sequencing of Canadian Saccharomyces cerevisiae strains isolated from spontaneous wine fermentations reveals a new Pacific West Coast Wine clade.G3 (Bethesda, Md.) · 2023Article
- Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity.Genome research · 2023Article
- Toxicity and assimilation of cellulosic copper nanoparticles require α-arrestins in S. cerevisiae.Metallomics : integrated biometal science · 2023Article
- SO2 and copper tolerance exhibit an evolutionary trade-off in Saccharomyces cerevisiae.PLoS genetics · 2023Article
- Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements.PLoS genetics · 2023Article
- Article
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Authors and funding
7 authors.
Funding
Abstract
An important issue in genome evolution is the mechanism by which tandem duplications are generated from single-copy genes. In the yeast Saccharomyces cerevisiae, most strains contain tandemly duplicated copies of CUP1, a gene that encodes a copper-binding metallothionein. By screening 101 natural isolates of S. cerevisiae, we identified five different types of CUP1-containing repeats, as well as strains that only had one copy of CUP1. A comparison of the DNA sequences of these strains indicates that the CUP1 tandem arrays were generated by unequal nonhomologous recombination events from strains that had one CUP1 gene.
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