ArticleCancer2015
Endoscopic ultrasonography in esophageal cancer leads to improved survival rates: results from a population-based study.
Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02887261 (Study on Indications of "Bard" PowerPort Isp Implantable Port), which is not on this map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study on Indications of "Bard" PowerPort Isp Implantable Port: Image Accuracy in Resectable Esophageal Cancer Patients
Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study.Oncotarget · 2016Trial
- Endoscopic Management of Esophageal Cancer.Cancers · 2022Review
- Article
- Focus on patients with early esophageal cancer-a prognostic nomogram.Translational cancer research · 2020Article
- Endoscopic Ultrasound Stagingof Esophageal Cancer.Gastroenterology & hepatology · 2020Article
- A nomogram for endoscopic screening in a high esophageal squamous cell cancer risk area: results from a population-based study.Cancer management and research · 2019Article
- Endoscopic ultrasound staging for early esophageal cancer: Are we denying patients neoadjuvant chemo-radiation?World journal of gastroenterology · 2017Article
- Routine staging with endoscopic ultrasound in patients with obstructing esophageal cancer and dysphagia rarely impacts treatment decisions.Surgical endoscopy · 2017Article
- Outcomes after endoscopic versus surgical therapy for early esophageal cancers in an older population.Gastrointestinal endoscopy · 2016Article
- Multidisciplinary management for esophageal and gastric cancer.Cancer management and research · 2016Review
- Pretreatment Dysphagia in Esophageal Cancer Patients May Eliminate the Need for Staging by Endoscopic Ultrasonography.The Annals of thoracic surgery · 2016Article
- Value of two-phase dynamic multidetector computed tomography in differential diagnosis of post-inflammatory strictures from esophageal cancer.World journal of gastroenterology · 2015Article
- Quality indicators for EUS.The American journal of gastroenterology · 2015Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundThe advantages of endoscopic ultrasound (EUS) and computed tomography (CT)-positron emission tomography (PET) with respect to survival for esophageal cancer patients are unclear. This study aimed to assess the effects of EUS, CT-PET, and their combination on overall survival with respect to cases not receiving these procedures.
methodsPatients who were ≥66 years old when diagnosed with esophageal cancer were identified in the Surveillance, Epidemiology, and End Results-Medicare linked database. Cases were split into 4 analytic groups: EUS only (n = 318), CT-PET only (n = 853), EUS+CT-PET (n = 189), and no EUS or CT-PET (n = 2439). Survival times were estimated with the Kaplan-Meier method and were compared with the log-rank test for each group versus the no EUS or CT-PET group. Multivariate Cox proportional hazards models were used to compare 1-, 3-, and 5-year survival rates.
resultsKaplan-Meier analyses showed that EUS, CT-PET, and EUS+CT-PET patients had improved survival for all stages (with the exception of stage 0 disease) in comparison with patients undergoing no EUS or CT-PET. Receipt of EUS increased the likelihood of receiving endoscopic therapies, esophagectomy, and chemoradiation. Multivariate Cox proportional hazards models showed that receipt of EUS was a significant predictor of improved 1- (hazard ratio [HR], 0.49; 95% confidence interval [CI], 0.39-0.59; P < .0001), 3- (HR, 0.57; 95% CI, 0.48-0.66; P < .0001), and 5-year survival (HR, 0.59; 95% CI, 0.50-0.68). Similar results were noted when the results were stratified on the basis of histology and for the CT-PET and EUS+CT-PET groups.
conclusionsReceipt of either EUS or CT-PET alone in esophageal cancer patients was associated with improved 1-, 3-, and 5-year survival. Future studies should identify barriers to the dissemination of these staging modalities.
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