Evidence map›Paper›PMID 25234952›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2014

Total thyroidectomy is associated with increased prevalence of permanent hypoparathyroidism.

Ireneusz Nawrot, Aneta Pragacz, Krzysztof Pragacz, Wiesław Grzesiuk, Marcin Barczyński

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  6. Article
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  9. Article
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  12. Article
  13. Article
  14. Parathyroid autotransplantation in thyroid surgery.Langenbeck's archives of surgery · 2018
    Review
  15. Article
  16. Article
  17. Better consenting for thyroidectomy: who has an increased risk of postoperative hypocalcaemia?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Article
  18. The Tubercle of Zuckerkandl : An Important Landmark Revisited.Indian journal of surgical oncology · 2016
    Article
  19. Article
  20. Association between decreased serum parathyroid hormone after total thyroidectomy and persistent hypoparathyroidism.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ireneusz NawrotDepartment Of General, Vascular and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland.
Aneta PragaczDistrict Endocrine Clinic, Independent Public Healthcare Institution, Staszów, Poland.
Krzysztof PragaczDepartment of General Surgery, Independent Public Healthcare Institution, Staszów, Poland.
Wiesław GrzesiukEndocrine Clinic - Medical Center, Medical University of Warsaw, Warsaw, Poland.
Marcin BarczyńskiDepartment of Endocrine Surgery, Third Chair of General Surgery, Jagiellonian University Medical College, Cracow, Poland.
Jagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid disorders are very common in adults. Despite advances in conservative management, surgery remains a treatment modality of choice in many cases. The mortality and morbidity of thyroidectomy are low, but long-term postoperative hypoparathyroidism (HPT) remains a prominent complication of the procedure. The aim of this study was to assess the incidence of permanent HPT and identify the risk factors for this complication in a cohort of post-thyroidectomy patients followed at a District Endocrine Clinic. MATERIAL AND

methodsThis was a retrospective analysis of 401 patients followed up at a Regional/District Endocrine Clinic, who had undergone thyroid surgery in the years 1993-2011. The percentage of patients with permanent (>12 months) HPT was the primary endpoint of the study. The statistically analyzed data of patients with permanent HPT versus the remaining patients free from postoperative complications included their demographic data, indications for surgical treatment of their thyroid disorder, and extent of the thyroid resection. The risk factors for postoperative hypoparathyroidism were assessed using logistic regression analysis.

resultsPermanent HPT following surgery on the thyroid gland occurred in 8.5% of the patients. It was more frequent following total thyroidectomy (20.2%) than near-total thyroidectomy (6.7%) or subtotal thyroidectomy (4.2%); p<0.0001. A multivariate statistical regression analysis demonstrated that primary total thyroidectomy was a significant risk factor for permanent HPT (OR 6.5; 95% CI: 2.9-14.4; p<0.0001).

conclusionsTotal thyroidectomy was associated with increased prevalence of permanent hypoparathyroidism when compared to less extensive thyroid resection modes in patients with benign thyroid diseases.

Indexed as

AdolescentAdultAgedAged, 80 and overDemographyFemaleHumansHypoparathyroidismIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceThyroidectomyYoung Adult

Identifiers

PMID25234952
PMCPMC4179543
OpenAlexW2152351678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.