Evidence map›Paper›PMID 25234439›Full record

ArticleThe British journal of nutrition2014

A modified Mediterranean diet score is associated with a lower risk of incident metabolic syndrome over 25 years among young adults: the CARDIA (Coronary Artery Risk Development in Young Adults) study.

Lyn M Steffen, Linda Van Horn, Martha L Daviglus, Xia Zhou, Jared P Reis, Catherine M Loria, David R Jacobs, Kiyah J Duffey

Open access · bronzeAbstract read
In one paragraph

Article in The British journal of nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Pooled it
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  17. Diet and metabolic syndrome: a narrative review.Internal and emergency medicine · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Lyn M SteffenDivision of Epidemiology and Community Health, University of Minnesota School of Public Health,1300 South Second Street, Suite 300,Minneapolis,MN55454,USA.
Linda Van HornNorthwestern University Feinberg School of Medicine,Chicago,IL,USA.
Martha L DaviglusUniversity of Illinois at Chicago, College of Medicine,Chicago,IL,USA.
Xia ZhouDivision of Epidemiology and Community Health, University of Minnesota School of Public Health,1300 South Second Street, Suite 300,Minneapolis,MN55454,USA.
Jared P ReisNational Heart, Lung, and Blood Institute, National Institutes of Health,Bethesda,MD,USA.
Catherine M LoriaNational Heart, Lung, and Blood Institute, National Institutes of Health,Bethesda,MD,USA.
David R JacobsDivision of Epidemiology and Community Health, University of Minnesota School of Public Health,1300 South Second Street, Suite 300,Minneapolis,MN55454,USA.
Kiyah J DuffeyDepartment of Human Nutrition,Foods and Exercise, Virginia Tech,Blacksburg,VA,USA.
University of Minnesota · USMinnesota Department of Health · USNational Heart Lung and Blood Institute · USNational Institutes of Health · USNorthwestern University · USUniversity of Illinois Chicago · USVirginia Tech · US

Funding

VASCULAR CALCIUM--AN EPIDEMIOLOGIC STUDYR01HL048050 · NHLBI · UNIVERSITY OF IOWA · PI MAHONEY, LARRY T · 1992 to 2004
$3.0M
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR01HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1998 to 2006
$1.3M
CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048047 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 1985 to 2000
$171k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048049 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1985 to 2000
$71k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
REGULATION OF LUNG SURFACTANT PROTEIN B GENE EXPRESSIONR29HL048048 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI BOGGARAM, VIJAYAKUMAR · 1993 to 1997
–
RETROVIRAL TRANSDUCTION OF CLASS I MHC GENER01HL048049 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SACHS, DAVID H · 1993 to 1997
–
CARDIA-ECHOCARDIOGRAPHY READINGN01HC045134 · HC · UNIVERSITY OF CALIFORNIA IRVINE · PI GARDIN, JULIUS M · 1994 to 2000
–
NHLBI NIH HHS N01 HC045134NHLBI NIH HHS N01 HC048047NHLBI NIH HHS N01 HC048048NHLBI NIH HHS N01 HC048049NHLBI NIH HHS N01 HC048050NHLBI NIH HHS N01 HC095095NHLBI NIH HHS N01-HC-45134NHLBI NIH HHS N01-HC-48047NHLBI NIH HHS N01-HC-48048NHLBI NIH HHS N01-HC-48049NHLBI NIH HHS N01-HC-95095
6 · The paper itself

Abstract

The Mediterranean diet has been reported to be inversely associated with incident metabolic syndrome (MetSyn) among older adults; however, this association has not been studied in young African American and white adults. The objective of the present study was to evaluate the association of a modified Mediterranean diet (mMedDiet) score with the 25-year incidence of the MetSyn in 4713 African American and white adults enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) study. A diet history questionnaire was used to assess dietary intake at baseline, year 7 and year 20 and a mMedDiet score was created. Cardiovascular risk factors were measured at multiple examinations over 25 years. The MetSyn was defined according to the National Cholesterol Education Program Adult Treatment Panel III (ATP III) criteria. Cox proportional-hazards regression analysis was use to evaluate associations for incident MetSyn across the mMedDiet score categories adjusting for demographic characteristics, lifestyle factors and BMI. Higher mMedDiet scores represented adherence to a dietary pattern rich in fruit, vegetables, whole grains, nuts and fish, but poor in red and processed meat and snack foods. The incidence of MetSyn components (abdominal obesity, elevated TAG concentrations and low HDL-cholesterol concentrations) was lower in those with higher mMedDiet scores than in those with lower scores. Furthermore, the incidence of the MetSyn was lower across the five mMedDiet score categories; the hazard ratios and 95 % CI from category 1 to category 5 were 1·0; 0·94 (0·76, 1·15); 0·84 (0·68, 1·04); 0·73 (0·58, 0·92); and 0·72 (0·54, 0·96), respectively (P trend= 0·005). These findings suggest that the risk of developing the MetSyn is lower when consuming a diet rich in fruit, vegetables, whole grains, nuts and fish.

Indexed as

Diet, MediterraneanAdolescentAdultCardiovascular DiseasesCholesterol, HDLCoronary VesselsFemaleHumansIncidenceMaleMetabolic SyndromeObesity, AbdominalProportional Hazards ModelsSurveys and QuestionnairesTriglyceridesYoung AdultCholesterol, HDLTriglycerides

Identifiers

PMID25234439
PMCPMC5607033
OpenAlexW2152783682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.