Evidence map›Paper›PMID 25234331›Full record

ArticleEpidemiology and infection2015

Seroepidemiology of varicella-zoster virus in Korean adolescents and adults using fluorescent antibody to membrane antigen test.

S B Han, K R Kang, D H Huh, H C Lee, J H Kim, J H Kang, S H Ma

Open access · hybridAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

S B HanDepartment of Pediatrics,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
K R KangVaccine Bio Research Institute,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
D H HuhVaccine Bio Research Institute,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
H C LeeVaccine Bio Research Institute,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
J H KimDepartment of Pediatrics,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
J H KangDepartment of Pediatrics,College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea.
S H MaDepartment of Pediatrics,Changwon Fatima Hospital,Changwon,Republic of Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a cross-sectional seroepidemiological study in 2012-2013 to determine the seroprevalence of varicella-zoster virus (VZV) in adolescents and adults living in Korea, where varicella vaccination has been recommended universally at age 12-15 months since 2005. Residual serum samples were collected from 1196 healthy adults and adolescents aged ⩾10 years between November 2012 and March 2013. The fluorescent antibody to membrane antigen (FAMA) test and enzyme-linked immunosorbent assay (ELISA) were performed to determine the seroprevalence of VZV. The seroprevalences of VZV were compared between six age groups: 10-19, 20-29, 30-39, 40-49, 50-59, and ⩾60 years. The seroprevalence of VZV in the entire study cohort was 99·1% according to the FAMA test and 93·1% as determined by ELISA. The seroprevalences of the six age groups were as follows: 96·0%, 99·5%, 99·5%, 99·5%, 100%, and 100%, respectively, by the FAMA test, and 83·3%, 93·0%, 93·0%, 97·5%, 94·5%, and 97·5%, respectively, by ELISA. Seroprevalence increased significantly with age (P < 0·001); moreover, the seroprevalence in subjects aged 10-19 years was significantly lower than in other age groups (P < 0·001), as measured by both the FAMA test and ELISA. Thus, strategies to increase protective immunity against VZV in teenagers are necessary.

Indexed as

AdolescentAdultAntigens, ViralChickenpoxChickenpox VaccineChildCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleFluorescent Antibody TechniqueHerpesvirus 3, HumanHumansImmunologic TestsMaleMiddle AgedRepublic of KoreaAntigens, ViralChickenpox Vaccinevaricella-zoster virus

Identifiers

PMID25234331
PMCPMC4416359
OpenAlexW2165453001

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.