Evidence map›Paper›PMID 25234139›Full record

ArticleInternational wound journal2015

The enhanced healing of a high-risk, clean, sutured surgical incision by prophylactic negative pressure wound therapy as delivered by Prevena™ Customizable™: cosmetic and therapeutic results.

Alessandro Scalise, Caterina Tartaglione, Elisa Bolletta, Roberto Calamita, Giovanni Nicoletti, Marina Pierangeli, Luca Grassetti, Giovanni Di Benedetto

Registry-linked trialOpen access · greenAbstract readCase Reports
In one paragraph

Article in International wound journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04434820 (External Negative Pressure Dressing System), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04434820 nacompletednot on this mapstarted 2020, after this paper: background citation

External Negative Pressure Dressing System (ENPDS) vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.

TypeinterventionalSponsorAin Shams Maternity HospitalRan2020 to 2021Enrolled260ConditionsWound DehiscenceArmsExternal negative pressure dressing system (Yuwell 7E-A portable suction unit)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Cellular benefits of single-use negative pressure wound therapy demonstrated in a novel ex vivo human skin wound model.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2021
    Article
  7. Article
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alessandro ScaliseDepartment of Plastic and Reconstructive Surgery, Università Politecnica delle Marche, Ancona, Italy.
Caterina Tartaglione
Elisa Bolletta
Roberto Calamita
Giovanni Nicoletti
Marina Pierangeli
Luca Grassetti
Giovanni Di Benedetto
Marche Polytechnic University · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the literature, incisional closure complications may range from postoperative surgical site infections, representing 17-22% of health care-associated infections, surgical wound dehiscence and formation of haematomas or seromas, and can lead to delayed or impaired incision healing. These kinds of situations are more common when wounds are closed under tension or in specific patient morbidities. Obesity, in particular, is associated with an impaired blood flow to tissues, predisposing the patient to increased risk of wound complications by various mechanisms. Incisional complications can become relevant economic burdens for health care systems because of an increase in the average length of hospital stay and readmissions, and additional medical and surgical procedures. Thus, a preventive therapy may have a critical role in the management of healing. Negative pressure wound therapy (NPWT) technology as delivered by Prevena™ Customizable™ (Kinetic Concepts Inc., San Antonio, TX) has recently been the focus of a new investigation, as a prophylactic measure to prevent complications via immediate postoperative application in high-risk, clean, closed surgical incisions. The authors present a 62-year-old class II obese female, who underwent bilateral inguinal dermolipectomy. Prophylactic NPWT as delivered by Prevena™ was performed successfully over surgical incisions. Cosmetic and therapeutic results are shown.

Indexed as

Equipment DesignFemaleHumansLipectomyMiddle AgedNegative-Pressure Wound TherapyObesity, MorbidSurgical Wound DehiscenceSurgical Wound InfectionWound HealingNegative pressure wound therapySurgical incisionSurgical wound infectionWound healing

Identifiers

PMID25234139
PMCPMC7950834
OpenAlexW1975106886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.