Evidence map›Paper›PMID 25232850›Full record

ReviewGenetics in medicine : official journal of the American College of Medical Genetics2015

Genomic screening of the general adult population: key concepts for assessing net benefit with systematic evidence reviews.

Anya E R Prince, Jonathan S Berg, James P Evans, Daniel E Jonas, Gail Henderson

Abstract readReview
In one paragraph

Review in Genetics in medicine : official journal of the American College of Medical Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Population genomic screening of all young adults in a health-care system: a cost-effectiveness analysis.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Article
  10. Age and perceived risks and benefits of preventive genomic screening.Genetics in medicine : official journal of the American College of Medical Genetics · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. The promise and peril of genomic screening in the general population.Genetics in medicine : official journal of the American College of Medical Genetics · 2016
    Article
  15. Review
  16. Can targeted genetic testing offer useful health information to adoptees?Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Article
  17. Looking for Trouble and Finding It.The American journal of bioethics : AJOB · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anya E R PrinceCenter for Genomics and Society, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000000200867881
Jonathan S Berg1] Center for Genomics and Society, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [2] Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [3] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [4] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
James P Evans1] Center for Genomics and Society, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [2] Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [3] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [4] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Daniel E Jonas1] Center for Genomics and Society, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [2] Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [3] Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Gail Henderson1] Center for Genomics and Society, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA [2] Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

North Carolina Clinical Genomic Evaluation by Next-gen Exome Sequencing 2U01HG006487 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERG, JONATHAN S, POWELL, BRADFORD C. · 2012 to 2021
$22.7M
Center for Genomics and SocietyP50HG004488 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HENDERSON, GAIL E · 2007 to 2017
$12.6M
NHGRI NIH HHS P50 HG004488NHGRI NIH HHS P50HG004488NHGRI NIH HHS U01 HG006487NHGRI NIH HHS U01HG006487
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultGenetic TestingGenetic VariationGenomicsHumansMass ScreeningPenetrancePopulation SurveillancePrevalence

Identifiers

PMID25232850
PMCPMC4387105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.