ArticlePloS one2014
Genome-wide identification and expression analysis of NBS-encoding genes in Malus x domestica and expansion of NBS genes family in Rosaceae.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
55 citing papers in PubMed, 91 citations in OpenAlex.
- Genome-Wide Characterization of Citrus NBS-LRR Genes and Integrative Analysis of a Candidate Gene Associated with Alternaria Brown Spot-Related QTL.Plants (Basel, Switzerland) · 2026Article
- Comparative analysis of PRR receptors and R genes reveals structural and functional divergence between wild, ancestral, and commercial citrus species.BMC genomics · 2026Article
- Genome-wide characterization of NBS-encoding genes inFrontiers in genetics · 2026Article
- Article
- Salicylic Acid-Induced Expression Profiles of LRR and LRR-RLK Candidate Genes ModulatePlants (Basel, Switzerland) · 2024Article
- Parental assigned chromosomes for cultivated cacao provides insights into genetic architecture underlying resistance to vascular streak dieback.The plant genome · 2024Article
- Genome-wide identification, and gene expression analysis of NBS-LRR domain containing R genes inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Constitutive Overexpression of an NB-ARC Gene from Wild ChineseInternational journal of molecular sciences · 2024Article
- Phenotyping, genetics, and "-omics" approaches to unravel and introgress enhanced resistance against apple scab (Horticulture research · 2024Article
- Genome-wide identification and characterization of NBLRR genes in finger millet (Eleusine coracana L.) and their expression in response to Magnaporthe grisea infection.BMC plant biology · 2024Article
- Evolutionary analysis of TIR- and non-TIR-NBS-LRR disease resistance genes in wild strawberries.Frontiers in plant science · 2024Article
- The mMolecular plant pathology · 2023Article
- Genome-Wide Identification and Expression Analysis of the TIR-NBS-LRR Gene Family and Its Response to Fungal Disease in Rose (Biology · 2023Article
- Comprehensive Analysis and Functional Verification of theInternational journal of molecular sciences · 2023Article
- Identification, characterization, and validation of NBS-encoding genes in grass pea.Frontiers in genetics · 2023Article
- Analysis ofPlants (Basel, Switzerland) · 2022Article
- Engineering drought and salinity tolerance traits in crops through CRISPR-mediated genome editing: Targets, tools, challenges, and perspectives.Plant communications · 2022Review
- Genome-wide analysis of NBS-LRR genes in Rosaceae species reveals distinct evolutionary patterns.Frontiers in genetics · 2022Article
- Different scales of gene duplications occurring at different times have jointly shaped the NBS-LRR genes in Prunus species.Molecular genetics and genomics : MGG · 2022Article
- Genome-wide comparative analysis of the nucleotide-binding site-encoding genes in fourFrontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nucleotide binding site leucine-rich repeats (NBS-LRR) disease resistance proteins play an important role in plant defense against pathogen attack. A number of recent studies have been carried out to identify and characterize NBS-LRR gene families in many important plant species. In this study, we identified NBS-LRR gene family comprising of 1015 NBS-LRRs using highly stringent computational methods. These NBS-LRRs were characterized on the basis of conserved protein motifs, gene duplication events, chromosomal locations, phylogenetic relationships and digital gene expression analysis. Surprisingly, equal distribution of Toll/interleukin-1 receptor (TIR) and coiled coil (CC) (1 ∶ 1) was detected in apple while the unequal distribution was reported in majority of all other known plant genome studies. Prediction of gene duplication events intriguingly revealed that not only tandem duplication but also segmental duplication may equally be responsible for the expansion of the apple NBS-LRR gene family. Gene expression profiling using expressed sequence tags database of apple and quantitative real-time PCR (qRT-PCR) revealed the expression of these genes in wide range of tissues and disease conditions, respectively. Taken together, this study will provide a blueprint for future efforts towards improvement of disease resistance in apple.
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