Evidence map›Paper›PMID 25232830›Full record

ArticlePloS one2014

Coverage and timing of children's vaccination: an evaluation of the expanded programme on immunisation in The Gambia.

Susana Scott, Aderonke Odutola, Grant Mackenzie, Tony Fulford, Muhammed O Afolabi, Yamundow Lowe Jallow, Momodou Jasseh, David Jeffries, Bai Lamin Dondeh, Stephen R C Howie and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04029454 (Neovac 2 Burkina Faso), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04029454 nacompletednot on this mapstarted 2020, after this paper: background citation

Neovac 2 Burkina Faso: Impact of the Integration of Hepatitis B Birth Dose Vaccine Into the Infant Immunization Schedule: a Mixed Methods Study Including a Cluster-randomized Trial, an Anthropological Study and an Economic Evaluation

TypeinterventionalSponsorInstitut PasteurRan2020 to 2023Enrolled10,000ConditionsHepatitis BArmsbirth dose vaccination against hepatitis B strategy
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. The Enterics for Global Health (EFGH)Open forum infectious diseases · 2024
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  14. Risk factors associated with non-vaccination in Gambian children: a population-based cohort study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Susana ScottMedical Research Council Unit, Fajara, The Gambia; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Aderonke OdutolaMedical Research Council Unit, Fajara, The Gambia.
Grant MackenzieMedical Research Council Unit, Fajara, The Gambia.
Tony FulfordMedical Research Council Unit, Fajara, The Gambia; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Muhammed O AfolabiMedical Research Council Unit, Fajara, The Gambia.
Yamundow Lowe JallowMinistry of Health and Social Welfare Government of The Gambia, The Quadrangle, Banjul, The Gambia.
Momodou JassehMedical Research Council Unit, Fajara, The Gambia.
David JeffriesMedical Research Council Unit, Fajara, The Gambia.
Bai Lamin DondehMedical Research Council Unit, Fajara, The Gambia.
Stephen R C HowieMedical Research Council Unit, Fajara, The Gambia.
Umberto D'AlessandroMedical Research Council Unit, Fajara, The Gambia.

Funding

Medical Research Council MC_UP_1003/1Medical Research Council MC_UP_A900_1116Medical Research Council MC_UP_A900_1119Medical Research Council MC_UP_A900_1123
6 · The paper itself

Abstract

objectiveTo evaluate the coverage and timeliness of the Expanded Programme on Immunisation (EPI) in The Gambia.

methodsVaccination data were obtained between January 2005 and December 2012 from the Farafenni Health and Demographic Surveillance System (FHDSS), the Basse Health and Demographic Surveillance System (BHDSS), the Kiang West Demographic surveillance system (KWDSS), a cluster survey in the more urban Western Health Region (WR) and a cross sectional study in four clinics in the semi-urban Greater Banjul area of WR. Kaplan-Meier survival function was used to estimate the proportion vaccinated by age and to assess timeliness to vaccination.

findingsBCG vaccine uptake was over 95% in all regions. Coverage of DPT1 ranged from 93.2% in BHDSS to 99.8% in the WR. Coverage decreased with increasing number of DPT doses; DPT3 coverage ranged from 81.7% in BHDSS to 99.0% in WR. Measles vaccination coverage ranged from 83.3% in BHDSS to 97.0% in WR. DPT4 booster coverage was low and ranged from 43.9% in the WR to 82.8% in KWDSS. Across all regions, delaying on previous vaccinations increased the likelihood of being delayed for the subsequent vaccination.

conclusionsThe Gambia health system achieves high vaccine coverage in the first year of life. However, there continues to be a delay to vaccination which may impact on the introduction of new vaccines. Examples of effectively functioning EPI programmes such as The Gambia one may well be important models for other low income countries struggling to achieve high routine vaccination coverage.

Indexed as

Immunization ScheduleAge DistributionBCG VaccineChild, PreschoolCross-Sectional StudiesDiphtheria-Tetanus-Pertussis VaccineFemaleGambiaHumansInfantMaleMass VaccinationMeasles VaccineMedication AdherenceNational Health ProgramsBCG VaccineDiphtheria-Tetanus-Pertussis VaccineMeasles Vaccine

Identifiers

PMID25232830
PMCPMC4169419

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.