Evidence map›Paper›PMID 25232540›Full record

ReviewFrontiers in bioengineering and biotechnology2014

Bacterial sigma factors as targets for engineered or synthetic transcriptional control.

Lakshmi Tripathi, Yan Zhang, Zhanglin Lin

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Evaluating EcxR for Its Possible Role inInternational journal of molecular sciences · 2022
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Rewiring the specificity of extracytoplasmic function sigma factors.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Duration of Heat Stress Effect on Invasiveness ofBioMed research international · 2018
    Article
  17. Article
  18. Overexpression of the primary sigma factor geneMetabolic engineering communications · 2017
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lakshmi TripathiDepartment of Chemical Engineering, Tsinghua University , Beijing , China.
Yan ZhangDepartment of Chemical Engineering, Tsinghua University , Beijing , China.
Zhanglin LinDepartment of Chemical Engineering, Tsinghua University , Beijing , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sigma (σ) factors are the predominant constituents of transcription regulation in bacteria. σ Factors recruit the core RNA polymerase to recognize promoters with specific DNA sequences. Recently, engineering of transcriptional regulators has become a significant tool for strain engineering. The present review summarizes the recent advances in σ factor based engineering or synthetic design. The manipulation of σ factors presents insights into the bacterial stress tolerance and metabolite productivity. We envision more synthetic design based on σ factors that can be used to tune the regulatory network of bacteria.

Indexed as

bacterial stress toleranceextremophilesigma factorstrain engineeringsynthetic biology

Identifiers

PMID25232540
PMCPMC4153023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.