Evidence map›Paper›PMID 25232528›Full record

ReviewWorld journal of orthopedics2014

Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications.

Lili Magyari, Dalma Varszegi, Erzsebet Kovesdi, Patricia Sarlos, Bernadett Farago, Andras Javorhazy, Katalin Sumegi, Zsolt Banfai, Bela Melegh

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of orthopedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

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  10. Synergism between chikungunya virus infection and rheumatoid arthritis on cytokine levels: Clinical implications?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Lili MagyariLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Dalma VarszegiLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Erzsebet KovesdiLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Patricia SarlosLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Bernadett FaragoLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Andras JavorhazyLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Katalin SumegiLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Zsolt BanfaiLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Bela MeleghLili Magyari, Erzsebet Kovesdi, Katalin Sumegi, Zsolt Banfai, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease, resulting in a chronic, systemic inflammatory disorder. It may affect many tissues and organs, but it primarily affects the flexible joints. In clinical practice patient care generates many questions about diagnosis, prognosis, and treatment. It is challenging for health care specialists to keep up to date with the medical literature. This review summarizes the pathogenesis, the polymorphisms of interleukin and interleukin genes and the standard available and possible future immunologic targets for RA treatment. The identification of disease-associated interleukin and interleukin receptor genes can provide precious insight into the genetic variations prior to disease onset in order to identify the pathways important for RA pathogenesis. The knowledge of the complex genetic background may prove useful for developing novel therapies and making personalized medicine based on the individual's genetics.

Indexed as

Immunologic targetsInterleukinsPolymorphismsRheumatoid arthritisTherapy

Identifiers

PMID25232528
PMCPMC4133458
OpenAlexW2317266260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.