Evidence map›Paper›PMID 25232230›Full record

ReviewWorld journal of gastroenterology2014

Extraintestinal manifestations of Helicobacter pylori: a concise review.

Frank Wong, Erin Rayner-Hartley, Michael F Byrne

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. A Significant Association between Type 1 Diabetes andMedicina (Kaunas, Lithuania) · 2024
    Pooled it
  2. Gut and liver · 2019
    Pooled it
  3. Article
  4. Review
  5. Association betweenThe Journal of international medical research · 2026
    Article
  6. World journal of hepatology · 2025
    Article
  7. Article
  8. Elevated fasting glucose levels associated withJournal of medicine and life · 2025
    Observational
  9. The Controversies in the Relationship BetweenJournal of clinical medicine · 2025
    Review
  10. Correlations BetweenLife (Basel, Switzerland) · 2025
    Article
  11. Observational
  12. Article
  13. Assessment ofHeliyon · 2024
    Article
  14. Article
  15. Article
  16. Antibiotic Resistance, Susceptibility Testing and Stewardship inInternational journal of molecular sciences · 2023
    Review
  17. Review
  18. Helicobacter pylori infection.Nature reviews. Disease primers · 2023
    Review
  19. Relationship betweenFrontiers in cellular and infection microbiology · 2023
    Article
  20. Children (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Frank WongFrank Wong, Erin Rayner-Hartley, Michael F Byrne, Division of Gastroenterology, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
Erin Rayner-HartleyFrank Wong, Erin Rayner-Hartley, Michael F Byrne, Division of Gastroenterology, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
Michael F ByrneFrank Wong, Erin Rayner-Hartley, Michael F Byrne, Division of Gastroenterology, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated with H. pylori infection include those from hematologic, cardiopulmonary, metabolic, neurologic, and dermatologic systems. The aim of this article is to provide a concise review of the evidence that supports or refutes the associations of H. pylori and its proposed extraintestinal manifestations. Based on data from the literature, PUD, mucosal associated lymphoid tumors lymphoma, and gastric adenocarcinoma has well-established links. Current evidence most supports extraintestinal manifestations with H. pylori in immune thrombocytopenic purpura, iron deficiency anemia, urticaria, Parkinson's, migraines and rosacea; however, there is still plausible link with other diseases that requires further research.

Indexed as

AnimalsHelicobacter InfectionsHelicobacter pyloriHumansPrognosisRisk FactorsImmune thrombocytopenic purpuraIron deficiencyMigraineRosaceaUrticaria

Identifiers

PMID25232230
PMCPMC4161781
OpenAlexW2028634769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.