ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2014
Decline of serum CA724 as a probable predictive factor for tumor response during chemotherapy of advanced gastric carcinoma.
Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Current and evolving practices of carbohydrate antigens in gastric cancer: a narrative review.Translational cancer research · 2025Review
- Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer.World journal of gastrointestinal oncology · 2024Article
- Determination of serum CA724 levels using fluorescence immunochromatography.BMC biotechnology · 2023Article
- A New Method for Early Screening of Gastric Cancer (G17 and CA724 Dual-Labeled Time-Resolved Fluorescence Immunoassay).Computational and mathematical methods in medicine · 2022Article
- CA724 predicts overall survival in locally advanced gastric cancer patients with neoadjuvant chemotherapy.BMC cancer · 2021Article
- CA724 Predicts Tumor Regression Grade in Locally Advanced Gastric Cancer Patients with Neoadjuvant Chemotherapy.Journal of Cancer · 2021Article
- Risk Factors and Their Diagnostic Values for Ocular Metastases in Gastric Adenocarcinoma.Cancer management and research · 2021Article
- Urachal carcinoma: Impact of recurrence pattern and lymphadenectomy on long-term outcomes.Cancer medicine · 2020Article
- The prognostic value of preoperative serum CA724 for CEA-normal colorectal cancer patients.PeerJ · 2020Article
- Detection of circulating stage III-IV gastric cancer tumor cells based on isolation by size of epithelial tumor: using the circulating tumor cell biopsy technology.Translational cancer research · 2019Article
- Glycopatterns and Glycoproteins Changes in MCN and SCN: A Prospective Cohort Study.BioMed research international · 2019Article
- Multiple cytokine profiling in serum for early detection of gastric cancer.World journal of gastroenterology · 2018Article
- Highly Expressed Granulocyte Colony-Stimulating Factor (G-CSF) and Granulocyte Colony-Stimulating Factor Receptor (G-CSFR) in Human Gastric Cancer Leads to Poor Survival.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Nomograms for predicting the prognostic value of serological tumor biomarkers in colorectal cancer patients after radical resection.Scientific reports · 2017Article
- Prognostic value of serum tumor abnormal protein in gastric cancer patients.Molecular and clinical oncology · 2016Article
- Article
- CA724 is a novel factor for predicting the unresectability in pancreatic adenocarcinoma.International journal of clinical and experimental pathology · 2015Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the predictive value of decline in the serum level of carbohydrate antigen 724 (CA724) on tumor response during the chemotherapy in patients with advanced gastric carcinoma (GC).
methodsThe serum CA724 level was determined by electrochemiluminescence immunoassay, while the objective response rate (ORR) was assessed according to response evaluation criteria in solid tumors (RECIST). The association of the changes of serum concentration of CA724 with ORR was analyzed.
resultsThe ORR in CA724 (pretreatment serum level) high and low groups was 32.3% (20/62) and 52.8% (19/36), respectively (P=0.045). The relationship between the reduction of CA724 and the ORR was statistically significant (P=0.044). Receiver operating characteristic (ROC) curve established the best cutoff value of the decrease ratio of CA724 as 20.5%.
conclusionsCA724 decline seems to indicate chemotherapy efficacy in patients with advanced GC, and an average drop of 20.5% in serum CA724 appears to predict the sensitivity to chemotherapy.
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