Evidence map›Paper›PMID 25232131›Full record

ArticleProceedings. Biological sciences2014

Conserved patterns of incomplete reporting in pre-vaccine era childhood diseases.

Christian E Gunning, Erik Erhardt, Helen J Wearing

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Pertussis vaccines, epidemiology and evolution.Nature reviews. Microbiology · 2024
    Review
  4. Evidence of cryptic incidence in childhood diseases.Proceedings. Biological sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christian E GunningDepartment of Biology, University of New Mexico, Albuquerque, NM, USA xian@unm.edu.
Erik ErhardtDepartment of Mathematics and Statistics, University of New Mexico, Albuquerque, NM, USA.
Helen J WearingDepartment of Biology, University of New Mexico, Albuquerque, NM, USA Department of Mathematics and Statistics, University of New Mexico, Albuquerque, NM, USA.

Funding

UNM COBRE: THEORETICAL STUDY OF SPECIFICITY OF RNA SILENCING MECHANISMP20RR018754 · NCRR · UNIVERSITY OF NEW MEXICO · PI LOKER, ERIC SAMUEL · 2003 to 2011
$16.7M
Integrated, Interdisciplinary, Inter-university PHD Program Computational BiologyT32EB009414 · NIBIB · UNIVERSITY OF NEW MEXICO · PI SMITH, FELISA ANNAMARIE · 2009 to 2013
$989k
NCRR NIH HHS P20 RR018754NCRR NIH HHS P20RR018754NIBIB NIH HHS T32 EB009414NIBIB NIH HHS T32EB009414
6 · The paper itself

Abstract

Incomplete observation is an important yet often neglected feature of observational ecological timeseries. In particular, observational case report timeseries of childhood diseases have played an important role in the formulation of mechanistic dynamical models of populations and metapopulations. Yet to our knowledge, no comprehensive study of childhood disease reporting probabilities (commonly referred to as reporting rates) has been conducted to date. Here, we provide a detailed analysis of measles and whooping cough reporting probabilities in pre-vaccine United States cities and states, as well as measles in cities of England and Wales. Overall, we find the variability between locations and diseases greatly exceeds that between methods or time periods. We demonstrate a strong relationship within location between diseases and within disease between geographical areas. In addition, we find that demographic covariates such as ethnic composition and school attendance explain a non-trivial proportion of reporting probability variation. Overall, our findings show that disease reporting is both variable and non-random and that completeness of reporting is influenced by disease identity, geography and socioeconomic factors. We suggest that variations in incomplete observation can be accounted for and that doing so can reveal ecologically important features that are otherwise obscured.

Indexed as

ChildChild, PreschoolDemographyDisease NotificationEnglandFemaleGeographyHumansInfantMaleMeaslesPopulation SurveillanceProbabilityTime FactorsUnited StatesWalesdisease ecologydynamical systemsmeaslesobservation processreporting rateswhooping cough

Identifiers

PMID25232131
PMCPMC4211441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.