ArticleNucleic acids research2015
The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource.
Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- An integrated resource for systems-level analysis of aging hallmarks and associated genes.Biogerontology · 2026Article
- Lifespan stops at death, but when does healthspan stop?Biogerontology · 2026Article
- HK2-driven histone H3K18 lactylation promotes stromal cell senescence and decidualization deficiency in URSA via CUX1-mediated SASP factor transcription.Cellular & molecular biology letters · 2026Article
- Assessing tissue-specific gene expression of essential genes from human and mouse.Briefings in bioinformatics · 2025Article
- Multiomics of Aging and Aging-Related Diseases.International journal of molecular sciences · 2024Review
- A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment.Nature communications · 2024Article
- Attitudes towards Technology: Insights on Rarely Discussed Influences on Older Adults' Willingness to Adopt Active Assisted Living (AAL).International journal of environmental research and public health · 2024Article
- voyAGEr, a free web interface for the analysis of age-related gene expression alterations in human tissues.eLife · 2024Article
- Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1.Translational psychiatry · 2024Article
- Human Ageing Genomic Resources: updates on key databases in ageing research.Nucleic acids research · 2024Article
- AgeAnnoMO: a knowledgebase of multi-omics annotation for animal aging.Nucleic acids research · 2024Article
- Open Genes-a new comprehensive database of human genes associated with aging and longevity.Nucleic acids research · 2024Article
- Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome.PloS one · 2024Article
- How is Big Data reshaping preclinical aging research?Lab animal · 2023Review
- Chaotic aging: intrinsically disordered proteins in aging-related processes.Cellular and molecular life sciences : CMLS · 2023Article
- Computational screen to identify potential targets for immunotherapeutic identification and removal of senescence cells.Aging cell · 2023Article
- High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity.GeroScience · 2023Article
- AgeAnno: a knowledgebase of single-cell annotation of aging in human.Nucleic acids research · 2023Article
- A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes.iScience · 2022Article
- Machine learning-based predictions of dietary restriction associations across ageing-related genes.BMC bioinformatics · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Multiple studies characterizing the human ageing phenotype have been conducted for decades. However, there is no centralized resource in which data on multiple age-related changes are collated. Currently, researchers must consult several sources, including primary publications, in order to obtain age-related data at various levels. To address this and facilitate integrative, system-level studies of ageing we developed the Digital Ageing Atlas (DAA). The DAA is a one-stop collection of human age-related data covering different biological levels (molecular, cellular, physiological, psychological and pathological) that is freely available online (http://ageing-map.org/). Each of the >3000 age-related changes is associated with a specific tissue and has its own page displaying a variety of information, including at least one reference. Age-related changes can also be linked to each other in hierarchical trees to represent different types of relationships. In addition, we developed an intuitive and user-friendly interface that allows searching, browsing and retrieving information in an integrated and interactive fashion. Overall, the DAA offers a new approach to systemizing ageing resources, providing a manually-curated and readily accessible source of age-related changes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.