ArticleWorld journal of surgery2015
Intraoperative frozen section for the evaluation of extrathyroidal extension in papillary thyroid cancer.
Article in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- [Frozen section in oncologic endocrine surgery].Chirurgie (Heidelberg, Germany) · 2025Pooled it
- Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Pooled it
- Guideline for the Surgical Management of Locally Invasive Differentiated Thyroid Cancer From the Korean Society of Head and Neck Surgery.Clinical and experimental otorhinolaryngology · 2023Guideline
- The Diagnostic Performance of Ultrasonography in the Evaluation of Extrathyroidal Extension in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Current Evidence, Selective Indications, and the Role of Lymph-Node Assessment in Intraoperative Frozen Section in Thyroid Cancer Surgery: A Literature Review.Journal of clinical medicine · 2026Review
- Intraoperative frozen section for determining the extent of surgery in papillary thyroid carcinoma: comprehensive risk factor assessment.Gland surgery · 2023Article
- The Role of Frozen Section Examination in Thyroid Surgery.Sisli Etfal Hastanesi tip bulteni · 2023Review
- Preoperative Factors Associated with Extrathyroidal Extension in Papillary Thyroid Cancer.European thyroid journal · 2020Article
- Intraoperative measurement of thyroglobulin in lymph node aspirates for the detection of metastatic papillary thyroid carcinoma.OncoTargets and therapy · 2017Article
- Overexpression of long non-coding RNA NR_036575.1 contributes to the proliferation and migration of papillary thyroid cancer.Medical oncology (Northwood, London, England) · 2016Article
- Intraoperative surgical decision using intraoperative frozen section in papillary thyroid cancer: reply.World journal of surgery · 2015Article
- Intraoperative frozen section for the evaluation of extrathyroidal extension in papillary thyroid cancer.World journal of surgery · 2015Article
- Intrathyroidal tumors presenting with extranodal extension: what are we missing?Endocrine pathology · 2014Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated extrathyroidal extension (ETE) through frozen biopsy for intraoperative decision making in patients with papillary thyroid cancer (PTC).
methodsDuring the period of the study an operation was performed in 268 patients with PTC and ETE was evaluated using intraoperative frozen biopsies of thyroid tissue.
resultsExtrathyroidal extension was confirmed in 54 patients (20 %) on frozen biopsy. Fifty-three patients among 54 patients showing ETE on frozen biopsy were confirmed on permanent pathologic analysis. Accordingly, frozen biopsy had a sensitivity of 66 %, a specificity of 99 %, a positive predictive value of 98 %, and a negative predictive value of 87 %. Tumor size (OR 4.373; CI 2.257-8.475, p = <0.001) was an independent factor for predicting ETE on frozen biopsy.
conclusionsIntraoperative frozen biopsy can be an useful tool in identifying the presence of ETE. It can also help the operator decide the extent of surgery and central neck dissection in patients with PTC.
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