ArticleNPJ primary care respiratory medicine2014
Depression and heart failure associated with clinical COPD questionnaire outcome in primary care COPD patients: a cross-sectional study.
Article in NPJ primary care respiratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A randomized, parallel-group study to evaluate the efficacy of umeclidinium/vilanterol 62.5/25 μg on health-related quality of life in patients with COPD.International journal of chronic obstructive pulmonary disease · 2016Trial
- Impact Of Peak Oxygen Pulse On Patients With Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2019Article
- Assessing health-related quality of life in COPD: comparing generic and disease-specific instruments with focus on comorbidities.BMC pulmonary medicine · 2016Article
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5 authors.
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Abstract
backgroundImprovement in health-related quality of life (HRQoL) is one of the main goals in treating chronic obstructive pulmonary disease (COPD). Impaired HRQoL in COPD is associated with increased morbidity and mortality, hospitalisations and burden on our health-care system. The Clinical COPD Questionnaire (CCQ) is a validated, reliable, short questionnaire for the evaluation of disease-specific HRQoL in patients with COPD in primary care.
aimsTo investigate factors that might be associated with CCQ outcome in COPD in a primary care setting.
methodsIn a population of COPD patients in primary care, multiple regression analyses were used to assess associations between CCQ outcome and depression, heart failure, FEV1% predicted, FEV1/FVC, age, sex, body mass index and current smoking.
resultsData from 341 patients (mean age 68.1±10.3, COPD GOLD class I-III) were used for analyses. Together, heart failure and depression explained 23% of the variance in CCQ total score (P<0.001, N=93). Heart failure was most strongly associated with CCQ functional score (27% explained variance, P<0.001, N=100), whereas depression was most strongly associated with CCQ mental score (22% explained variance, P<0.001, N=93).
conclusionsCCQ outcomes are higher in COPD patients with heart failure and depression. These findings might imply that heart failure and depression affect HRQoL of patients with COPD, and thus emphasise the importance of a holistic approach of this complex disease, leading to a correct diagnosis of COPD and its comorbidities, to achieve better tailored treatment of chronic patients.
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