ArticleJournal of mathematical biology2015
On the eigenvalue effective size of structured populations.
Article in Journal of mathematical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Assessment of the Global Variance Effective Size of Subdivided Populations, and Its Relation to Other Effective Sizes.Acta biotheoretica · 2023Article
- Do estimates of contemporary effective population size tell us what we want to know?Molecular ecology · 2019Article
- Metapopulation effective size and conservation genetic goals for the Fennoscandian wolf (Canis lupus) population.Heredity · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A general theory is developed for the eigenvalue effective size (N(e)E) of structured populations in which a gene with two alleles segregates in discrete time. Generalizing results of Ewens (Theor Popul Biol 21:373-378, 1982), we characterize N(e)E in terms of the largest non-unit eigenvalue of the transition matrix of a Markov chain of allele frequencies. We use Perron-Frobenius Theorem to prove that the same eigenvalue appears in a linear recursion of predicted gene diversities between all pairs of subpopulations. Coalescence theory is employed in order to characterize this recursion, so that explicit novel expressions for N(e)E can be derived. We then study N(e)E asymptotically, when either the inverse size and/or the overall migration rate between subpopulations tend to zero. It is demonstrated that several previously known results can be deduced as special cases. In particular when the coalescence effective size N(e)C exists, it is an asymptotic version of N(e)E in the limit of large populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.